(2S,3R)-2-tert-butyldimethylsilyloxymethyl-3-hydroxymethyl-N-tosylaziridine

Base Information

Chemical Name:(2S,3R)-2-tert-butyldimethylsilyloxymethyl-3-hydroxymethyl-N-tosylaziridine
CAS No.:152984-30-0
Molecular Formula:C₁₇H₂₉NO₄SSi
Molecular Weight:371.573
Hs Code.:

Synonyms:(2S,3R)-2-tert-butyldimethylsilyloxymethyl-3-hydroxymethyl-N-tosylaziridine

Suppliers and Price of (2S,3R)-2-tert-butyldimethylsilyloxymethyl-3-hydroxymethyl-N-tosylaziridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2S,3R)-2-tert-butyldimethylsilyloxymethyl-3-hydroxymethyl-N-tosylaziridine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2S,3R)-2-tert-butyldimethylsilyloxymethyl-3-hydroxymethyl-N-tosylaziridine

There total 3 articles about (2S,3R)-2-tert-butyldimethylsilyloxymethyl-3-hydroxymethyl-N-tosylaziridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: Acetic acid (2R,3S)-3-(tert-butyl-dimethyl-silanyloxymethyl)-1-(toluene-4-sulfonyl)-aziridin-2-ylmethyl ester

: 152984-30-0
(2S,3R)-2-tert-butyldimethylsilyloxymethyl-3-hydroxymethyl-N-tosylaziridine

Guidance literature:: With potassium carbonate; In methanol; Yield given;
DOI:10.1016/S0040-4039(00)60694-9

Reference yield:

: 132835-12-2
Acetic acid (2R,3S)-3-hydroxymethyl-1-(toluene-4-sulfonyl)-aziridin-2-ylmethyl ester

: 152984-30-0
(2S,3R)-2-tert-butyldimethylsilyloxymethyl-3-hydroxymethyl-N-tosylaziridine

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine, 4-dimethylaminopyridine / CH₂Cl₂ / 1 h / Ambient temperature

2: potassium carbonate / methanol / 0.25 h / 0 °C

With dmap; potassium carbonate; triethylamine; In methanol; dichloromethane;
DOI:10.3987/COM-95-S76

Reference yield:

: 18162-48-6
tert-butyldimethylsilyl chloride

: 152984-30-0
(2S,3R)-2-tert-butyldimethylsilyloxymethyl-3-hydroxymethyl-N-tosylaziridine

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine, 4-dimethylaminopyridine / CH₂Cl₂ / 1 h / Ambient temperature

2: potassium carbonate / methanol / 0.25 h / 0 °C

With dmap; potassium carbonate; triethylamine; In methanol; dichloromethane;
DOI:10.3987/COM-95-S76