3-Phenyl-but-3-enoic acid isobutyl ester

Base Information

• Chemical Name: 3-Phenyl-but-3-enoic acid isobutyl ester
• CAS No.: 125289-53-4
• Molecular Formula: C₁₄H₁₈O₂
• Molecular Weight: 218.296
• Mol file: 125289-53-4.mol

Synonyms:3-Phenyl-but-3-enoic acid isobutyl ester

Chemical Property of 3-Phenyl-but-3-enoic acid isobutyl ester

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 3-Phenyl-but-3-enoic acid isobutyl ester

There total 3 articles about 3-Phenyl-but-3-enoic acid isobutyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

Carbonic acid isobutyl ester 2-phenyl-allyl ester (125289-59-0) → 3-Phenyl-but-3-enoic acid isobutyl ester (125289-53-4)

Guidance literature:

With palladium diacetate; carbon monoxide; triphenylphosphine; at 50 ℃; under 9120 Torr;

DOI:10.1016/0022-328X(89)87295-X

Reference yield:

3-hydroxy-2-phenylpropene (6006-81-1) → 3-Phenyl-but-3-enoic acid isobutyl ester (125289-53-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 68 percent / pyridine / diethyl ether / 1.) 0 deg C, 2 h, 2.) room temperature

2: 68 percent / CO, Pd(OAc)2, PPh₃ / 50 °C / 9120 Torr

With pyridine; palladium diacetate; carbon monoxide; triphenylphosphine; In diethyl ether;

DOI:10.1016/0022-328X(89)87295-X

Reference yield:

isobutyl chloroformate (543-27-1) → 3-Phenyl-but-3-enoic acid isobutyl ester (125289-53-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 68 percent / pyridine / diethyl ether / 1.) 0 deg C, 2 h, 2.) room temperature

2: 68 percent / CO, Pd(OAc)2, PPh₃ / 50 °C / 9120 Torr

With pyridine; palladium diacetate; carbon monoxide; triphenylphosphine; In diethyl ether;

DOI:10.1016/0022-328X(89)87295-X

upstream raw materials:

Carbonic acid isobutyl ester 2-phenyl-allyl ester

3-hydroxy-2-phenylpropene

isobutyl chloroformate