{3-[(2',6'-dimethylbiphenyl-3-yl)methoxy]bicyclo[4.2.0]octa-1,3,5-trien-7-yl}methanol

Base Information

Chemical Name:{3-[(2',6'-dimethylbiphenyl-3-yl)methoxy]bicyclo[4.2.0]octa-1,3,5-trien-7-yl}methanol
CAS No.:1359669-51-4
Molecular Formula:C₂₄H₂₄O₂
Molecular Weight:344.453
Hs Code.:

Synonyms:{3-[(2',6'-dimethylbiphenyl-3-yl)methoxy]bicyclo[4.2.0]octa-1,3,5-trien-7-yl}methanol

Suppliers and Price of {3-[(2',6'-dimethylbiphenyl-3-yl)methoxy]bicyclo[4.2.0]octa-1,3,5-trien-7-yl}methanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of {3-[(2',6'-dimethylbiphenyl-3-yl)methoxy]bicyclo[4.2.0]octa-1,3,5-trien-7-yl}methanol

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of {3-[(2',6'-dimethylbiphenyl-3-yl)methoxy]bicyclo[4.2.0]octa-1,3,5-trien-7-yl}methanol

There total 13 articles about {3-[(2',6'-dimethylbiphenyl-3-yl)methoxy]bicyclo[4.2.0]octa-1,3,5-trien-7-yl}methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 1359668-71-5
3-[(2',6'-dimethylbiphenyl-3-yl)methoxy]bicyclo[4.2.0]octa-1,3,5-triene-7-carboxylic acid

: 1359669-51-4
{3-[(2',6'-dimethylbiphenyl-3-yl)methoxy]bicyclo[4.2.0]octa-1,3,5-trien-7-yl}methanol

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 - 20 ℃; for 1h; Inert atmosphere;
DOI:10.1021/jm2012968

Reference yield:

: 242473-46-7
3-hydroxybicyclo[4.2.0]octa-1,3,5-triene-7-carbonitrile

: 1359669-51-4
{3-[(2',6'-dimethylbiphenyl-3-yl)methoxy]bicyclo[4.2.0]octa-1,3,5-trien-7-yl}methanol

Guidance literature:: Multi-step reaction with 3 steps

1: tributylphosphine; 1,1'-azodicarbonyl-dipiperidine / 20 °C

2: potassium hydroxide / ethanol; water / 69 h / 20 °C / Reflux

3: lithium aluminium tetrahydride / tetrahydrofuran / 1 h / 0 - 20 °C / Inert atmosphere

With lithium aluminium tetrahydride; tributylphosphine; potassium hydroxide; 1,1'-azodicarbonyl-dipiperidine; In tetrahydrofuran; ethanol; water; 1: Mitsunobu reaction;
DOI:10.1021/jm2012968

Reference yield:

: 691905-26-7
2',6'-dimethyl-[1,1'-biphenyl]-3-carbaldehyde

: 1359669-51-4
{3-[(2',6'-dimethylbiphenyl-3-yl)methoxy]bicyclo[4.2.0]octa-1,3,5-trien-7-yl}methanol

Guidance literature:: Multi-step reaction with 4 steps

1: sodium tetrahydroborate / tetrahydrofuran; 1,2-dimethoxyethane / 0 °C

2: tributylphosphine; 1,1'-azodicarbonyl-dipiperidine / 20 °C

3: potassium hydroxide / ethanol; water / 69 h / 20 °C / Reflux

4: lithium aluminium tetrahydride / tetrahydrofuran / 1 h / 0 - 20 °C / Inert atmosphere

With sodium tetrahydroborate; lithium aluminium tetrahydride; tributylphosphine; potassium hydroxide; 1,1'-azodicarbonyl-dipiperidine; In tetrahydrofuran; 1,2-dimethoxyethane; ethanol; water; 2: Mitsunobu reaction;
DOI:10.1021/jm2012968