(+/-)-3-trifluoroacetamido-1-(4,4'-dimethoxytriphenylmethyl)-2-propanediol

Base Information

Chemical Name:(+/-)-3-trifluoroacetamido-1-(4,4'-dimethoxytriphenylmethyl)-2-propanediol
CAS No.:125348-24-5
Molecular Formula:C₂₆H₂₆F₃NO₅
Molecular Weight:489.491
Hs Code.:

Synonyms:(+/-)-3-trifluoroacetamido-1-(4,4'-dimethoxytriphenylmethyl)-2-propanediol

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (+/-)-3-trifluoroacetamido-1-(4,4'-dimethoxytriphenylmethyl)-2-propanediol

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Technology Process of (+/-)-3-trifluoroacetamido-1-(4,4'-dimethoxytriphenylmethyl)-2-propanediol

There total 1 articles about (+/-)-3-trifluoroacetamido-1-(4,4'-dimethoxytriphenylmethyl)-2-propanediol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 40615-36-9
4,4'-dimethoxytrityl chloride

: 125348-23-4
N-(2,3-dihydroxypropyl)-2,2,2-trifluoroacetamide

: 125348-24-5
(+/-)-3-trifluoroacetamido-1-(4,4'-dimethoxytriphenylmethyl)-2-propanediol

Guidance literature:: With pyridine; at 20 ℃;
DOI:10.1016/S0040-4020(01)00409-4

Reference yield: 65.0%

: 2245-53-6
2,2'-[1,4-phenylenebis(oxy)]bisacetic acid

: 125348-24-5
(+/-)-3-trifluoroacetamido-1-(4,4'-dimethoxytriphenylmethyl)-2-propanediol

: (4-{2-[bis-(4-methoxy-phenyl)-phenyl-methoxy]-1-[(2,2,2-trifluoro-acetylamino)-methyl]-ethoxycarbonylmethoxy}-phenoxy)-acetic acid

Guidance literature:: 2,2'-[1,4-phenylenebis(oxy)]bisacetic acid; With diisopropyl-carbodiimide; In pyridine; N,N-dimethyl-formamide; at 20 ℃; for 1h;

(+/-)-3-trifluoroacetamido-1-(4,4'-dimethoxytriphenylmethyl)-2-propanediol; With dmap; In pyridine; N,N-dimethyl-formamide; at 20 ℃;
DOI:10.1016/S0040-4020(01)00409-4