Technology Process of C24H34N2O5
There total 5 articles about C24H34N2O5 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
C23H32N2O5;
With
sodium hexamethyldisilazane;
In
tetrahydrofuran;
at -78 ℃;
for 0.5h;
methyl iodide;
In
tetrahydrofuran;
at -78 ℃;
for 2h;
optical yield given as %de;
diastereoselective reaction;
DOI:10.1021/ol300342n
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: toluene-4-sulfonic acid / water; acetone / 0.33 h
2.1: sodium chlorite; sodium dihydrogen phosphate monohydrate; 2-methyl-but-2-ene / water; tert-butyl alcohol / 2.5 h
3.1: pivaloyl chloride; triethylamine / tetrahydrofuran / 3 h / -20 °C
3.2: 3.5 h / -20 - 20 °C
4.1: sodium hexamethyldisilazane / tetrahydrofuran / 0.5 h / -78 °C
4.2: 2 h / -78 °C
With
sodium chlorite; sodium dihydrogen phosphate monohydrate; 2-methyl-but-2-ene; sodium hexamethyldisilazane; pivaloyl chloride; toluene-4-sulfonic acid; triethylamine;
In
tetrahydrofuran; water; acetone; tert-butyl alcohol;
2.1: Pinnick oxidation;
DOI:10.1021/ol300342n
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: sodium chlorite; sodium dihydrogen phosphate monohydrate; 2-methyl-but-2-ene / water; tert-butyl alcohol / 2.5 h
2.1: pivaloyl chloride; triethylamine / tetrahydrofuran / 3 h / -20 °C
2.2: 3.5 h / -20 - 20 °C
3.1: sodium hexamethyldisilazane / tetrahydrofuran / 0.5 h / -78 °C
3.2: 2 h / -78 °C
With
sodium chlorite; sodium dihydrogen phosphate monohydrate; 2-methyl-but-2-ene; sodium hexamethyldisilazane; pivaloyl chloride; triethylamine;
In
tetrahydrofuran; water; tert-butyl alcohol;
1.1: Pinnick oxidation;
DOI:10.1021/ol300342n
