Biotin-PEG5-azide

Base Information

Chemical Name:Biotin-PEG5-azide
CAS No.:1163732-89-5
Molecular Formula:C₂₂H₄₀N₆O₇S
Molecular Weight:532.662
Hs Code.:

Synonyms:N-(17-azido-3,6,9,12,15-pentaoxaheptadecyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-pentanamide

Suppliers and Price of Biotin-PEG5-azide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

purepeg
(+)-Biotin-PEG5-CH2CH2-azide min.97%
50 mg
$ 162.00

BroadPharm
Biotin-PEG5-azide 98%
500 MG
$ 680.00

Acrotein
Biotin-PEG5-CH2CH2N3 97%
0.25g
$ 302.50

Total 10 raw suppliers

Chemical Property of Biotin-PEG5-azide

Chemical Property:

Purity/Quality:

98%,99%, ^*data from raw suppliers

(+)-Biotin-PEG5-CH2CH2-azide min.97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Description Biotin-PEG5-azideBiotin-PEG3-azide is a click chemistry biotinylation reagent that can react with alkyne molecule to form a stable triazole linkage.

Technology Process of Biotin-PEG5-azide

There total 2 articles about Biotin-PEG5-azide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 33755-53-2
D-(+)-biotin 2-nitrophenyl ester

: 516493-93-9
α-amino,ω-azido,α,ω-dideoxy-hexaethyleneglycol

: 1163732-89-5
N-(17-azido-3,6,9,12,15-pentaoxaheptadecyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-pentanamide

Guidance literature:: With triethylamine; In tetrahydrofuran; at 20 ℃; for 12h;
DOI:10.1038/s41467-019-09387-4

Reference yield: 57.0%

: 58-85-5,22879-79-4
biotin

: 516493-93-9
α-amino,ω-azido,α,ω-dideoxy-hexaethyleneglycol

: 1163732-89-5
N-(17-azido-3,6,9,12,15-pentaoxaheptadecyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-pentanamide

Guidance literature:: With 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride; In methanol; at 20 ℃;
DOI:10.1021/jo500376m

Reference yield: 89.0%

: 1163732-89-5
N-(17-azido-3,6,9,12,15-pentaoxaheptadecyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-pentanamide

: amino(((S)-5-amino-4-((S)-2-((S)-1-((2S,5S,8S)-2-(4-aminobutyl)-18-glycyl-8-isopropyl-5-(4-(isopropyl(phenethyl)amino)butyl)-4,7,10,13,16-pentaoxo-3,6,9,12,15,18-hexaazahenicos-20-ynoyl)pyrrolidine-2-carboxamido)-4-methylpentanamido)-5-oxopentyl)amino)methaniminium

: amino(((S)-5-amino-4-((S)-2-((S)-1-((2S,5S,8S)-20-amino-2-(4-aminobutyl)-8-isopropyl-5-(4-(isopropyl(phenethyl)amino)butyl)-4,7,10,13,16,19-hexaoxo-18-((1-(19-oxo-23-((3aR,4R,6aS)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-3,6,9,12,15-pentaoxa-18-azatricosyl)-1H-1,2,3-triazol-5-yl)methyl)-3,6,9,12,15,18-hexaazaicosanoyl)pyrrolidine-2-carboxamido)-4-methylpentanamido)-5-oxopentyl)amino)methaniminium

Guidance literature:: With copper(II) sulfate; sodium L-ascorbate; In water; N,N-dimethyl-formamide; at 20 ℃; for 2h;
DOI:10.1021/acs.jmedchem.1c00430