D-BIOTIN P-NITROPHENYL ESTER

Base Information

Chemical Name:D-BIOTIN P-NITROPHENYL ESTER
CAS No.:33755-53-2
Molecular Formula:C16H19N3O5S
Molecular Weight:365.41
Hs Code.:29349990
Mol file:33755-53-2.mol

Synonyms:(+)-Biotin 4-nitrophenyl ester;1H-Thieno(3,4-d)imidazole-4-pentanoic acid, hexahydro-2-oxo-, 4-nitrophenyl ester, (3aS,4S,6aR)-;1H-Thieno(3,4-d)imidazole-4-pentanoic acid, hexahydro-2-oxo-, 4-nitrophenyl ester, (3aS-(3aalpha,4beta,6aalpha))-;Biotin-p-nitrophenyl ester;

Suppliers and Price of D-BIOTIN P-NITROPHENYL ESTER

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
BNP
200ul
$ 432.00

Usbiological
Biotin p-nitrophenyl ester
250mg
$ 340.00

TCI Chemical
(+)-Biotin 4-Nitrophenyl Ester >98.0%(HPLC)(N)
200mg
$ 115.00

Sigma-Aldrich
Biotin-ONp Novabiochem?
1 g
$ 196.00

Sigma-Aldrich
Biotin-ONp Novabiochem . CAS 33755-53-2, molar mass 365.41 g/mol., Novabiochem
8510270001
$ 189.00

Sigma-Aldrich
Monoclonal Anti-NPPB antibody produced in mouse clone 8D5B4C11, ascites fluid
100 μL
$ 424.00

Sigma-Aldrich
Monoclonal Anti-NPPB antibody produced in mouse clone 9H6B4, ascites fluid
100 μL
$ 424.00

Sigma-Aldrich
Monoclonal Anti-NPPB antibody produced in mouse clone 2D11, purified immunoglobulin, buffered aqueous solution
100ug
$ 424.00

Sigma-Aldrich
(+)-Biotin 4-nitrophenyl ester 98%
100mg
$ 84.60

purepeg
(+)-Biotin-ONP min.95%
1 g
$ 100.00

Total 51 raw suppliers

Chemical Property of D-BIOTIN P-NITROPHENYL ESTER

Chemical Property:

Vapor Pressure:2.03E-16mmHg at 25°C
Melting Point:163-165 ºC
Refractive Index:1.583
Boiling Point:642.9 °C at 760 mmHg
PKA:13.89±0.40(Predicted)
Flash Point:342.6 °C
PSA：138.55000
Density:1.326 g/cm³
LogP:3.40680
Storage Temp.:−20°C
Solubility.:methanol: soluble25mg/mL, clear, colorless to greenish-yellow

Purity/Quality:

99%, ^*data from raw suppliers

BNP ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Safety Statements: 22-24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Uses (+)-Biotin 4-nitrophenyl ester may be used in the preparation of biotin tagged ARC (adenosine-oligoarginine conjugate) derivative during cellular protein uptake studies. It may also be used to prepare biotinylated quinazoline derivatives, which shows inhibitory activities against VEGFR-2 (vascular endothelial growth factor receptor-2) tyrosine kinase. (+)-Biotin 4-nitrophenyl ester undergoes hydrolysis in the presence of Na[17O]H to form [17O2]biotin, which can be used in solid-state 17O NMR spectroscopic experiments to analyze large protein-ligand complexes. For research use only. Not for use in diagnostic procedures.Brain natriuretic peptide EIA Kit has been used to measure brain natriuretic peptide (BNP) secreted in human neonatal ventricular cardiomyocyte culture.

Technology Process of D-BIOTIN P-NITROPHENYL ESTER

There total 4 articles about D-BIOTIN P-NITROPHENYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 100-02-7,78813-13-5,89830-32-0
4-nitro-phenol

: 58-85-5,22879-79-4
biotin

: 33755-53-2
D-(+)-biotin 2-nitrophenyl ester

Guidance literature:: With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide; at 20 ℃; for 24h;
DOI:10.1021/acs.bioconjchem.7b00110

Reference yield:

: 62062-42-4
5-((3aS)-2-oxo-1-trifluoroacetyl-(3ar,6ac)-hexahydro-thieno[3,4-d]imidazol-4t-yl)-pentanoic acid 4-nitro-phenyl ester

: 33755-53-2
D-(+)-biotin 2-nitrophenyl ester

Guidance literature:: With ethanol; Heating;
DOI:10.1021/ja00443a040

Reference yield:

: 658-78-6
1-nitro-4-trifluoroacetoxy-benzene

: 33755-53-2
D-(+)-biotin 2-nitrophenyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 4-nitro-phenol, Py / 50 °C

2: aq. EtOH / Heating

With pyridine; 4-nitro-phenol; ethanol;
DOI:10.1021/ja00443a040