2-(3-Pyridyl)-1,3-thiazole-4-carboxylic acid

Base Information

Chemical Name:2-(3-Pyridyl)-1,3-thiazole-4-carboxylic acid
CAS No.:39067-29-3
Molecular Formula:C9H6N2O2S
Molecular Weight:206.225
Hs Code.:2934100090
European Community (EC) Number:670-393-7
DSSTox Substance ID:DTXSID00353048
Wikidata:Q82130503
Mol file:39067-29-3.mol

Synonyms:39067-29-3;2-(3-pyridyl)-1,3-thiazole-4-carboxylic acid;2-(Pyridin-3-yl)thiazole-4-carboxylic acid;2-(pyridin-3-yl)-1,3-thiazole-4-carboxylic acid;2-Pyridin-3-yl-thiazole-4-carboxylic acid;4-thiazolecarboxylic acid, 2-(3-pyridinyl)-;2-pyridin-3-yl-1,3-thiazole-4-carboxylic acid;2-(3-PYRIDYL)THIAZOLE-4-CARBOXYLIC ACID;2-(3-Pyridyl)Thiazole-4-Carboxylic Acid, 97%;CDS1_000037;Maybridge1_002325;DivK1c_001077;SCHEMBL369871;HMS548B15;DTXSID00353048;MFCD00052304;STK530141;AKOS005463094;AB02182;AS-5182;CCG-274083;SDCCGMLS-0065977.P001;2-(3-pyridyl)thiazol-4-carboxylic acid;BP-10663;2-(3-pyridyl)-thiazole-4-carboxylic acid;2-(3-pyridinyl)-4-thiazolylcarboxylic acid;2-(Pyridin-3-yl)thiazole-4-carboxylicacid;CS-0156822;FT-0608563;D82874;EN300-178638;2-(PYRID-3-YL)THIAZOLE-4-CARBOXYLIC ACID;A824393;J-505831;2-(3-PYRIDINYL)-1,3-THIAZOLE-4-CARBOXYLIC ACID;Z381355510

Suppliers and Price of 2-(3-Pyridyl)-1,3-thiazole-4-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-(3-Pyridyl)-1,3-thiazole-4-carboxylicAcid
50mg
$ 45.00

SynQuest Laboratories
2-(Pyridin-3-yl)-1,3-thiazole-4-carboxylic acid
250 mg
$ 77.00

Matrix Scientific
2-Pyridin-3-yl-thiazole-4-carboxylic acid 95+%
10g
$ 1543.00

Matrix Scientific
2-Pyridin-3-yl-thiazole-4-carboxylic acid 95+%
5g
$ 962.00

Matrix Scientific
2-Pyridin-3-yl-thiazole-4-carboxylic acid 95+%
1g
$ 246.00

Crysdot
2-(Pyridin-3-yl)thiazole-4-carboxylicacid 97%
25g
$ 410.00

Chemenu
2-Pyridin-3-yl-thiazole-4-carboxylicacid 97%
25g
$ 383.00

Atlantic Research Chemicals
2-(3-Pyridyl)-1,3-thiazole-4-carboxylicacid 95%
10gm:
$ 417.08

Apolloscientific
2-(Pyridin-3-yl)-1,3-thiazole-4-carboxylicacid
250mg
$ 70.00

American Custom Chemicals Corporation
2-(3-PYRIDYL)-1,3-THIAZOLE-4-CARBOXYLIC ACID 95.00%
1G
$ 717.21

Total 24 raw suppliers

Chemical Property of 2-(3-Pyridyl)-1,3-thiazole-4-carboxylic acid

Chemical Property:

Vapor Pressure:2.87E-09mmHg at 25°C
Melting Point:283 °C
Refractive Index:1.651
Boiling Point:460.3 °C at 760 mmHg
PKA:3.29±0.10(Predicted)
Flash Point:232.2 °C
PSA：91.32000
Density:1.44 g/cm³
LogP:1.90330
Storage Temp.:2-8°C
XLogP3:1.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:206.01499861
Heavy Atom Count:14
Complexity:225

Purity/Quality:

97% ^*data from raw suppliers

2-(3-Pyridyl)-1,3-thiazole-4-carboxylicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36/37/39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CN=C1)C2=NC(=CS2)C(=O)O
Uses 2-(3-Pyridyl)thiazole-4-carboxylic acid is a pyridylthiazole compound that has use in a variety of diverse applications from highly luminescent heterocyclic compounds to potential antiulcer drugs, to the formation of double and triple helicates with Cu(II) and to the mesoscopically ordered pH-responsive hybrid materials.

Technology Process of 2-(3-Pyridyl)-1,3-thiazole-4-carboxylic acid

There total 4 articles about 2-(3-Pyridyl)-1,3-thiazole-4-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 39067-28-2
ethyl 2-(pyridin-3-yl) thiazole-4-carboxylate

: 39067-29-3
2-(pyridin-3-yl)-1,3-thiazole-4-carboxylic acid

Guidance literature:: ethyl 2-(pyridin-3-yl) thiazole-4-carboxylate; With methanol; potassium hydroxide; In tetrahydrofuran; for 3h;

With hydrogenchloride; In tetrahydrofuran; methanol; water;

Reference yield: 52.0%

: 116055-57-3
2-[3]pyridyl-thiazole-4-carboxylic acid ethyl ester; hydrobromide

: 39067-29-3
2-(pyridin-3-yl)-1,3-thiazole-4-carboxylic acid

Guidance literature:: 2-[3]pyridyl-thiazole-4-carboxylic acid ethyl ester; hydrobromide; With water; sodium hydroxide; at 20 ℃; for 2h;

With hydrogenchloride; In water; pH=4; Cooling with ice;

Reference yield:

: 4621-66-3
thionicotinamide

: 39067-29-3
2-(pyridin-3-yl)-1,3-thiazole-4-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: ethanol / 6 h / Reflux

2: lithium hydroxide / ethanol / 1 h / 20 °C

With lithium hydroxide; In ethanol;
DOI:10.1021/acs.jmedchem.9b01313