1-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]-2,2-dihydroxyethanone

Base Information

Chemical Name:1-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]-2,2-dihydroxyethanone
CAS No.:1361570-62-8
Molecular Formula:C₁₅H₁₂FN₃O₃
Molecular Weight:301.277
Hs Code.:

Synonyms:1-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]-2,2-dihydroxyethanone

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]-2,2-dihydroxyethanone

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Technology Process of 1-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]-2,2-dihydroxyethanone

There total 2 articles about 1-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]-2,2-dihydroxyethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1361570-61-7
1-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]ethanone

: 1361570-62-8
1-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]-2,2-dihydroxyethanone

Guidance literature:: With hydrogen bromide; In water; dimethyl sulfoxide; at 55 ℃; for 5h;

Reference yield:

: 256376-65-5
1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carbonitrile

: 1361570-62-8
1-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]-2,2-dihydroxyethanone

Guidance literature:: Multi-step reaction with 2 steps

1: diethyl ether / 21 h / 20 °C / Inert atmosphere; Reflux

2: hydrogen bromide / dimethyl sulfoxide; water / 5 h / 55 °C

With hydrogen bromide; In diethyl ether; water; dimethyl sulfoxide;