4,4,5,5-tetramethyl-2-[(4-tert-butylphenyl)methyl]-1,3,2-dioxaborolane

Base Information

• Chemical Name: 4,4,5,5-tetramethyl-2-[(4-tert-butylphenyl)methyl]-1,3,2-dioxaborolane
• CAS No.: 1242770-19-9
• Molecular Formula: C₁₇H₂₇BO₂
• Molecular Weight: 274.211
• Mol file: 1242770-19-9.mol

Synonyms:4,4,5,5-tetramethyl-2-[(4-tert-butylphenyl)methyl]-1,3,2-dioxaborolane

Chemical Property of 4,4,5,5-tetramethyl-2-[(4-tert-butylphenyl)methyl]-1,3,2-dioxaborolane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4,4,5,5-tetramethyl-2-[(4-tert-butylphenyl)methyl]-1,3,2-dioxaborolane

There total 10 articles about 4,4,5,5-tetramethyl-2-[(4-tert-butylphenyl)methyl]-1,3,2-dioxaborolane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

4-tert-butylbenzyl chloride (19692-45-6) + bis(pinacol)diborane (73183-34-3) → 4,4,5,5-tetramethyl-2-[(4-tert-butylphenyl)methyl]-1,3,2-dioxaborolane (1242770-19-9)

Guidance literature:

With iron(III)-acetylacetonate; magnesium; In tetrahydrofuran; at 0 ℃; for 3h; Inert atmosphere;

Reference yield: 76.0%

1-(bromomethyl)-4-(1,1-dimethylethyl)benzene (18880-00-7) + 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane (25015-63-8) → 4,4,5,5-tetramethyl-2-[(4-tert-butylphenyl)methyl]-1,3,2-dioxaborolane (1242770-19-9)

Guidance literature:

With magnesium; triethylamine; In tetrahydrofuran; for 15h; Inert atmosphere; Reflux;

DOI:10.1021/ja1052973

Reference yield: 71.0%

2,3-dimethyl-2,3-butane diol (76-09-5) + p-tert-butylphenylboronic acid (123324-71-0) + diazomethyl-trimethyl-silane (18107-18-1) → 4,4,5,5-tetramethyl-2-[(4-tert-butylphenyl)methyl]-1,3,2-dioxaborolane (1242770-19-9)

Guidance literature:

p-tert-butylphenylboronic acid; diazomethyl-trimethyl-silane; In 1,4-dioxane; hexane; at 40 ℃; for 4h;

2,3-dimethyl-2,3-butane diol; With tetrabutyl ammonium fluoride; In tetrahydrofuran; 1,4-dioxane; hexane; water; at 40 ℃; for 4h;

upstream raw materials:

1-(bromomethyl)-4-(1,1-dimethylethyl)benzene

4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane

4-tert-butyltoluene

bis(pinacol)diborane

Downstream raw materials:

4-t-butylphenylacetic acid

C₃₁H₃₇N₃O₃