2-[3-(Trifluoromethyl)phenyl]benzaldehyde

Base Information

Chemical Name:2-[3-(Trifluoromethyl)phenyl]benzaldehyde
CAS No.:223575-93-7
Molecular Formula:C₁₄H₉F₃O
Molecular Weight:250.22
Hs Code.:2913000090
European Community (EC) Number:673-276-9
DSSTox Substance ID:DTXSID40362699
Wikidata:Q82146020
Mol file:223575-93-7.mol

Synonyms:223575-93-7;2-[3-(trifluoromethyl)phenyl]benzaldehyde;3'-trifluoromethylbiphenyl-2-carbaldehyde;3'-(Trifluoromethyl)-[1,1'-biphenyl]-2-carbaldehyde;3'-Trifluoromethyl-biphenyl-2-carbaldehyde;3'-(trifluoromethyl)[1,1'-biphenyl]-2-carbaldehyde;SCHEMBL2478195;DTXSID40362699;MFCD03424643;AKOS000124529;NCGC00374019-01;3'-(trifluoromethyl)biphenyl-2-carbaldehyde;2-(4-CHLORO-PHENOXY)-ACETAMIDINEHCL;BB 0222577;FT-0644050;EN300-265679;A816148;3'-(trifluoromethyl)-1,1'-biphenyl-2-carbaldehyde;J-014665;3'-(trifluoromethyl)[1,1'-biphenyl]-2-carboxaldehyde;F9995-2398

Suppliers and Price of 2-[3-(Trifluoromethyl)phenyl]benzaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
3′-(Trifluoromethyl)-1,1′-biphenyl-2-carboxaldehyde 96%
1g
$ 109.00

Matrix Scientific
3'-(Trifluoromethyl)-[1,1'-biphenyl]-2-carbaldehyde 95+%
5g
$ 1174.00

Matrix Scientific
3'-(Trifluoromethyl)-[1,1'-biphenyl]-2-carbaldehyde 95+%
1g
$ 355.00

Matrix Scientific
3'-(Trifluoromethyl)-[1,1'-biphenyl]-2-carbaldehyde 95+%
2.500g
$ 776.00

Crysdot
3'-(Trifluoromethyl)-[1,1'-biphenyl]-2-carbaldehyde 95+%
10g
$ 427.00

CHESS?
AD002044:3'-Trifluoromethyl-biphenyl-2-carbaldehyde 95
1 g
$ 336.00

Chemenu
3''-(Trifluoromethyl)-[1,1''-biphenyl]-2-carbaldehyde 95%
10g
$ 403.00

American Custom Chemicals Corporation
3'-TRIFLUOROMETHYLBIPHENYL-2-CARBALDEHYDE 95.00%
1G
$ 1280.66

AK Scientific
3′-(Trifluoromethyl)-1,1′-biphenyl-2-carboxaldehyde
1g
$ 193.00

AHH
3-Trifluoromethylbiphenyl-2-carbaldehyde 98%
5g
$ 930.00

Total 11 raw suppliers

Chemical Property of 2-[3-(Trifluoromethyl)phenyl]benzaldehyde

Chemical Property:

Refractive Index:n20/D1.551
Boiling Point:339.0±42.0 °C(Predicted)
Flash Point:>110℃
PSA：17.07000
Density:1.281 g/mL at 25 °C
LogP:4.18490
Storage Temp.:2-8°C
XLogP3:3.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:250.06054939
Heavy Atom Count:18
Complexity:287

Purity/Quality:

98%min ^*data from raw suppliers

3′-(Trifluoromethyl)-1,1′-biphenyl-2-carboxaldehyde 96% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi,N,Xn
Statements: 22-36/38-51/53
Safety Statements: 26-61

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C(=C1)C=O)C2=CC(=CC=C2)C(F)(F)F

Technology Process of 2-[3-(Trifluoromethyl)phenyl]benzaldehyde

There total 5 articles about 2-[3-(Trifluoromethyl)phenyl]benzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 402-26-6
3-(trifluoromethyl)phenylmagnesium bromide

: 82632-38-0
N-tert-butyl-1-(2-methoxyphenyl)methanimine

: 223575-93-7
3'-(trifluoromethyl)-[1,1'-biphenyl]-2-carbaldehyde

Guidance literature:: N-tert-butyl-1-(2-methoxyphenyl)methanimine; With chromium dichloride; In tetrahydrofuran; at 25 ℃; for 0.0833333h; Schlenk technique; Inert atmosphere;

3-(trifluoromethyl)phenylmagnesium bromide; In tetrahydrofuran; at 25 ℃; for 5h; Schlenk technique; Inert atmosphere;

With hydrogenchloride; In tetrahydrofuran; water; at 25 ℃; for 3h; Schlenk technique; Inert atmosphere;
DOI:10.1021/jacs.5b08621

Reference yield: 68.0%

: 444-29-1
2-iodo(trifluoromethyl)benzene

: 18982-54-2
o-bromobenzyl alcohol

: 223575-93-7
3'-(trifluoromethyl)-[1,1'-biphenyl]-2-carbaldehyde

Guidance literature:: With norbornene; palladium diacetate; cesium pivalate; In N,N-dimethyl-formamide; at 105 ℃; for 24h; Inert atmosphere;
DOI:10.1021/ol302889t

Reference yield: 48.0%

: 1423-26-3
(meta-(trifluoromethyl)phenyl)boronic acid

: 6630-33-7
ortho-bromobenzaldehyde

: 223575-93-7
3'-(trifluoromethyl)-[1,1'-biphenyl]-2-carbaldehyde

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium phosphate monohydrate; In 1,2-dimethoxyethane; at 150 ℃; for 1.5h; under 4500.45 Torr; Microwave irradiation;
DOI:10.1016/j.tet.2011.02.026