Trifluoro-methanesulfonic acid 4-[1,3-dimethyl-1-(4-trifluoromethanesulfonyloxy-phenyl)-butyl]-phenyl ester

Base Information

• Chemical Name: Trifluoro-methanesulfonic acid 4-[1,3-dimethyl-1-(4-trifluoromethanesulfonyloxy-phenyl)-butyl]-phenyl ester
• CAS No.: 173315-00-9
• Molecular Formula: C₂₀H₂₀F₆O₆S₂
• Molecular Weight: 534.498
• Mol file: 173315-00-9.mol

Synonyms:Trifluoro-methanesulfonic acid 4-[1,3-dimethyl-1-(4-trifluoromethanesulfonyloxy-phenyl)-butyl]-phenyl ester

Chemical Property of Trifluoro-methanesulfonic acid 4-[1,3-dimethyl-1-(4-trifluoromethanesulfonyloxy-phenyl)-butyl]-phenyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of Trifluoro-methanesulfonic acid 4-[1,3-dimethyl-1-(4-trifluoromethanesulfonyloxy-phenyl)-butyl]-phenyl ester

There total 1 articles about Trifluoro-methanesulfonic acid 4-[1,3-dimethyl-1-(4-trifluoromethanesulfonyloxy-phenyl)-butyl]-phenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

trifluoromethylsulfonic anhydride (358-23-6) + 2,2-bis(4-hydroxy phenyl)-4-methyl pentane (6807-17-6) → Trifluoro-methanesulfonic acid 4-[1,3-dimethyl-1-(4-trifluoromethanesulfonyloxy-phenyl)-butyl]-phenyl ester (173315-00-9)

Guidance literature:

With pyridine; for 25h; Ambient temperature;

DOI:10.1021/ja00155a006

Reference yield: 74.0%

acrylic acid methyl ester (292638-85-8,9003-21-8,96-33-3) + Trifluoro-methanesulfonic acid 4-[1,3-dimethyl-1-(4-trifluoromethanesulfonyloxy-phenyl)-butyl]-phenyl ester (173315-00-9) → dimethyl 4,4'-(2-methylpent-4-ylidene)bis(cinnamate) (173315-02-1)

Guidance literature:

With (PPh₃)PdCl₂; triethylamine; lithium chloride; In N,N-dimethyl-formamide; at 70 ℃; for 10h;

DOI:10.1021/ja00155a006

Reference yield:

Trifluoro-methanesulfonic acid 4-[1,3-dimethyl-1-(4-trifluoromethanesulfonyloxy-phenyl)-butyl]-phenyl ester (173315-00-9) → 4,4'-(2-methylpent-4-ylidene)bis(dihydrocinnamic acid) (173314-93-7)

Guidance literature:

Multi-step reaction with 3 steps

1: 74 percent / (PPh₃)PdCl₂, LiCl, Et₃N / dimethylformamide / 10 h / 70 °C

2: 99 percent / H₂ / 5percent Pd/C / ethanol / 8 h / 30400 Torr / Ambient temperature

3: 99 percent / KOH / ethanol; tetrahydrofuran / 4 h / Ambient temperature

With potassium hydroxide; (PPh₃)PdCl₂; hydrogen; triethylamine; lithium chloride; palladium on activated charcoal; In tetrahydrofuran; ethanol; N,N-dimethyl-formamide;

DOI:10.1021/ja00155a006

upstream raw materials:

trifluoromethylsulfonic anhydride

2,2-bis(4-hydroxy phenyl)-4-methyl pentane

Downstream raw materials:

dimethyl 4,4'-(2-methylpent-4-ylidene)bis(cinnamate)

4,4'-(2-methylpent-4-ylidene)bis(dihydrocinnamic acid)

dimethyl 4,4'-(2-methylpeny-4-ylidene)bis(dihydrocinnamate)