tert-Butyl N-(2-aminomethylphenyl)carbamate

Base Information

Chemical Name:tert-Butyl N-(2-aminomethylphenyl)carbamate
CAS No.:849020-94-6
Molecular Formula:C12H18N2O2
Molecular Weight:222.287
Hs Code.:2924299090
European Community (EC) Number:687-407-2
DSSTox Substance ID:DTXSID50375437
Nikkaji Number:J2.864.143E
Wikidata:Q72509702
Mol file:849020-94-6.mol

Synonyms:849020-94-6;tert-Butyl N-(2-aminomethylphenyl)carbamate;tert-Butyl 2-(aminomethyl)phenylcarbamate;Tert-butyl N-[2-(aminomethyl)phenyl]carbamate;2-(tert-butoxycarbonylamino)benzylamine;(2-aminomethyl-phenyl)-carbamic acid tert-butyl ester;tert-Butyl (2-(aminomethyl)phenyl)carbamate;2-(Boc-amino)benzylamine;tert-Butyl [2-(aminomethyl)phenyl]carbamate;MFCD04037902;2-(aminomethyl)-1-n-boc-aniline;SCHEMBL1127904;2-(Aminomethyl)-N-Boc-aniline;DTXSID50375437;BFFRNSYPZZUZDR-UHFFFAOYSA-N;AKOS005146299;CS-W005861;SB39007;DS-14709;SY103916;FT-0651439;EN300-316931;O12084;J-524794

Suppliers and Price of tert-Butyl N-(2-aminomethylphenyl)carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
tert-Butyl2-(Aminomethyl)phenylcarbamate
500mg
$ 200.00

SynQuest Laboratories
2-(Aminomethyl)aniline, 1-Boc protected
5 g
$ 871.00

SynQuest Laboratories
2-(Aminomethyl)aniline, 1-Boc protected
1 g
$ 199.00

Sigma-Aldrich
2-(Boc-amino)benzylamine
1g
$ 118.00

Matrix Scientific
tert-Butyl 2-(aminomethyl)phenylcarbamate
500mg
$ 165.00

Matrix Scientific
tert-Butyl 2-(aminomethyl)phenylcarbamate
1g
$ 98.00

J&W Pharmlab
(2-Aminomethyl-phenyl)-carbamicacidtert-butylester 96%
500mg
$ 88.00

J&W Pharmlab
(2-Aminomethyl-phenyl)-carbamicacidtert-butylester 96%
1g
$ 98.00

J&W Pharmlab
(2-Aminomethyl-phenyl)-carbamicacidtert-butylester 96%
5g
$ 398.00

Crysdot
tert-ButylN-(2-aminomethylphenyl)carbamate 95+%
25g
$ 743.00

Total 34 raw suppliers

Chemical Property of tert-Butyl N-(2-aminomethylphenyl)carbamate

Chemical Property:

Boiling Point:299.5 °C at 760 mmHg
PKA:13.67±0.70(Predicted)
Flash Point:134.9 °C
PSA：64.35000
Density:1.12 g/cm³
LogP:3.26560
Storage Temp.:under inert gas (nitrogen or Argon) at 2–8 °C
XLogP3:1.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:222.136827821
Heavy Atom Count:16
Complexity:236

Purity/Quality:

97% ^*data from raw suppliers

tert-Butyl2-(Aminomethyl)phenylcarbamate ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn
Statements: 22-43
Safety Statements: 36/37

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NC1=CC=CC=C1CN
Uses Tert-Butyl 2-(aminomethyl)phenylcarbamate can be used as reactant for Two-step syntheses of fused quinoxaline-benzodiazepines and bis-benzodiazepines employing a double UDC (Ugi/Deprotect/Cyclize) Reactant for:Two-step syntheses of fused quinoxaline-benzodiazepines and bis-benzodiazepines employing a double UDC (Ugi/Deprotect/Cyclize) strategyPreparation of hydroquinazoline scaffolds via microwave-promoted Ugi reaction and cyclizationPreparation of pyrazinone inhibitors of mast cell tryptase

Technology Process of tert-Butyl N-(2-aminomethylphenyl)carbamate

There total 2 articles about tert-Butyl N-(2-aminomethylphenyl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 1244783-42-3
2-Boc-aminobenzyl-Cbz-amine

: 849020-94-6
tert-butyl (2-(aminomethyl)phenyl)carbamate

Guidance literature:: With palladium 10% on activated carbon; hydrogen; In methanol; at 20 ℃; under 2068.65 Torr;
DOI:10.1016/j.tetlet.2010.06.131