C₂₀H₃₁I₂NO₂

Base Information

• Chemical Name: C₂₀H₃₁I₂NO₂
• CAS No.: 1404213-20-2
• Molecular Formula: C₂₀H₃₁I₂NO₂
• Molecular Weight: 571.281
• Mol file: 1404213-20-2.mol

Synonyms:C₂₀H₃₁I₂NO₂

Chemical Property of C₂₀H₃₁I₂NO₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₀H₃₁I₂NO₂

There total 3 articles about C₂₀H₃₁I₂NO₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

n-dodecanoyl chloride (112-16-3) + tert-butyl 3,5-diiodophenyl-4-methoxy methylcarbamate (1372787-73-9) → C20H31I2NO2 (1404213-20-2)

Guidance literature:

tert-butyl 3,5-diiodophenyl-4-methoxy methylcarbamate; With trifluoroacetic acid; In dichloromethane; for 2h;

n-dodecanoyl chloride; With dmap; 1,8-diazabicyclo[5.4.0]undec-7-ene; triethylamine; In dichloromethane; at 20 ℃; Inert atmosphere;

DOI:10.1002/ejoc.201200655

Reference yield:

tert-butyl (4-hydroxybenzyl)carbamate (149505-94-2) → C20H31I2NO2 (1404213-20-2)

Guidance literature:

Multi-step reaction with 3 steps

1.1: sodium chlorite; sodium iodide / methanol; water

1.2: 20 °C

2.1: potassium carbonate / acetone / Inert atmosphere; Reflux

3.1: trifluoroacetic acid / dichloromethane / 2 h

3.2: 20 °C / Inert atmosphere

With sodium chlorite; potassium carbonate; trifluoroacetic acid; sodium iodide; In methanol; dichloromethane; water; acetone;

DOI:10.1002/ejoc.201200655

Reference yield:

tert-butyl 4-hydroxy-3,5-diiodobenzylcarbamate (1404213-19-9) → C20H31I2NO2 (1404213-20-2)

Guidance literature:

Multi-step reaction with 2 steps

1.1: potassium carbonate / acetone / Inert atmosphere; Reflux

2.1: trifluoroacetic acid / dichloromethane / 2 h

2.2: 20 °C / Inert atmosphere

With potassium carbonate; trifluoroacetic acid; In dichloromethane; acetone;

DOI:10.1002/ejoc.201200655

upstream raw materials:

tert-butyl (4-hydroxybenzyl)carbamate

tert-butyl 4-hydroxy-3,5-diiodobenzylcarbamate

n-dodecanoyl chloride

tert-butyl 3,5-diiodophenyl-4-methoxy methylcarbamate

Downstream raw materials:

C₂₂H₃₅I₂NO₃

C₃₂H₅₃NO₃Si₂

C₅₂H₆₉NO₃Si₂

C₄₆H₅₃NO₃