2-(4-Fluoro-3-methoxyphenyl)ethan-1-amine

Base Information

Chemical Name:2-(4-Fluoro-3-methoxyphenyl)ethan-1-amine
CAS No.:128495-48-7
Molecular Formula:C₉H₁₂FNO
Molecular Weight:169.199
Hs Code.:
European Community (EC) Number:853-908-1
ChEMBL ID:CHEMBL4550347
DSSTox Substance ID:DTXSID901293631

Synonyms:2-(4-fluoro-3-methoxyphenyl)ethan-1-amine;128495-48-7;2-(4-fluoro-3-methoxyphenyl)ethanamine;SCHEMBL1237469;CHEMBL4550347;DTXSID901293631;4-Fluoro-3-methoxybenzeneethanamine;AKOS006289895;AT23332;EN300-124895

Suppliers and Price of 2-(4-Fluoro-3-methoxyphenyl)ethan-1-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 2-(4-Fluoro-3-methoxyphenyl)ethan-1-amine

Chemical Property:

XLogP3:0.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:169.090292168
Heavy Atom Count:12
Complexity:132

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=C(C=CC(=C1)CCN)F

Technology Process of 2-(4-Fluoro-3-methoxyphenyl)ethan-1-amine

There total 9 articles about 2-(4-Fluoro-3-methoxyphenyl)ethan-1-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: (E)-1-fluoro-2-methoxy-4-(2-nitrovinyl)benzene

: 128495-48-7
2-(4-fluoro-3-methoxyphenyl)ethan-1-amine

Guidance literature:: With lithium aluminium tetrahydride; sulfuric acid; In tetrahydrofuran; 2-methyltetrahydrofuran; at 20 ℃; for 0.0833333h; Inert atmosphere; Reflux;

Reference yield: 54.0%

: 128495-47-6
2-(4-fluoro-3-methoxyphenyl)nitroethylene

: 128495-48-7
2-(4-fluoro-3-methoxyphenyl)ethan-1-amine

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; for 12h; Ambient temperature;
DOI:10.1021/jm00171a014

Reference yield:

: 1-fluoro-2-methoxy-4-(2-nitrovinyl)benzene

: 128495-48-7
2-(4-fluoro-3-methoxyphenyl)ethan-1-amine

Guidance literature:: 1-fluoro-2-methoxy-4-(2-nitrovinyl)benzene; With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 - 20 ℃; for 2.5h; Heating / reflux;

With water; In tetrahydrofuran; at 0 - 20 ℃;