(3S)-4-(2-bromo-5-hydroxy-4-methoxyphenyl)-3-methoxycarbonylbutanoic acid

Base Information

Chemical Name:(3S)-4-(2-bromo-5-hydroxy-4-methoxyphenyl)-3-methoxycarbonylbutanoic acid
CAS No.:193679-29-7
Molecular Formula:C₁₃H₁₅BrO₆
Molecular Weight:347.163
Hs Code.:

Synonyms:(3S)-4-(2-bromo-5-hydroxy-4-methoxyphenyl)-3-methoxycarbonylbutanoic acid

Suppliers and Price of (3S)-4-(2-bromo-5-hydroxy-4-methoxyphenyl)-3-methoxycarbonylbutanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (3S)-4-(2-bromo-5-hydroxy-4-methoxyphenyl)-3-methoxycarbonylbutanoic acid

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (3S)-4-(2-bromo-5-hydroxy-4-methoxyphenyl)-3-methoxycarbonylbutanoic acid

There total 4 articles about (3S)-4-(2-bromo-5-hydroxy-4-methoxyphenyl)-3-methoxycarbonylbutanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 193679-43-5
(3S)-4-(3-hydroxy-4-methoxyphenyl)-3-methoxycarbonylbutanoic acid

: 193679-29-7
(3S)-4-(2-bromo-5-hydroxy-4-methoxyphenyl)-3-methoxycarbonylbutanoic acid

Guidance literature:: With bromine; acetic acid;
DOI:10.1021/jo9710994

Reference yield:

: 193679-28-6
(E)-4-(3-hydroxy-4-methoxyphenyl)-3-methoxycarbonyl-3-butenoic acid

: 193679-29-7
(3S)-4-(2-bromo-5-hydroxy-4-methoxyphenyl)-3-methoxycarbonylbutanoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: hydrogen / chlororhodium(I) (4R,5R)-MOD-DIOP complex / tetrahydrofuran; methanol / 7 h / 20 °C

2: bromine; acetic acid / 0.17 h / 20 °C

With hydrogen; bromine; acetic acid; chlororhodium(I) (4R,5R)-MOD-DIOP; In tetrahydrofuran; methanol; 1: Catalytic hydrogenation / 2: Bromination;
DOI:10.1021/jo990905z

Reference yield:

: 621-59-0
isovanillin

: 193679-29-7
(3S)-4-(2-bromo-5-hydroxy-4-methoxyphenyl)-3-methoxycarbonylbutanoic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 68 percent / sodium methoxide / methanol / 6 h / Heating

2: hydrogen / chlororhodium(I) (4R,5R)-MOD-DIOP complex / tetrahydrofuran; methanol / 7 h / 20 °C

3: bromine; acetic acid / 0.17 h / 20 °C

With hydrogen; bromine; sodium methylate; acetic acid; chlororhodium(I) (4R,5R)-MOD-DIOP; In tetrahydrofuran; methanol; 1: Condensation / 2: Catalytic hydrogenation / 3: Bromination;
DOI:10.1021/jo990905z