2(S)-tert-butoxy-carbonyl-amino-4(S)-isopropyl-5-(p-tert-butyl-phenyl)-pentanal

Base Information

Chemical Name:2(S)-tert-butoxy-carbonyl-amino-4(S)-isopropyl-5-(p-tert-butyl-phenyl)-pentanal
CAS No.:172900-84-4
Molecular Formula:C₂₃H₃₇NO₃
Molecular Weight:375.552
Hs Code.:

Synonyms:2(S)-tert-butoxy-carbonyl-amino-4(S)-isopropyl-5-(p-tert-butyl-phenyl)-pentanal

Suppliers and Price of 2(S)-tert-butoxy-carbonyl-amino-4(S)-isopropyl-5-(p-tert-butyl-phenyl)-pentanal

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of 2(S)-tert-butoxy-carbonyl-amino-4(S)-isopropyl-5-(p-tert-butyl-phenyl)-pentanal

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of 2(S)-tert-butoxy-carbonyl-amino-4(S)-isopropyl-5-(p-tert-butyl-phenyl)-pentanal

There total 4 articles about 2(S)-tert-butoxy-carbonyl-amino-4(S)-isopropyl-5-(p-tert-butyl-phenyl)-pentanal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 98-51-1
4-tert-butyltoluene

: 172900-84-4
2(S)-tert-butoxy-carbonyl-amino-4(S)-isopropyl-5-(p-tert-butyl-phenyl)-pentanal

Guidance literature:: Multi-step reaction with 5 steps

1: NBS / CCl₄

2: 1.) LiHMDS, 2.) n-BuLi, LiAlH₄, BnSH / 1.) THF

3: NBS, PPh₃ / CH₂Cl₂

5: DIBAH / toluene

With N-Bromosuccinimide; lithium aluminium tetrahydride; n-butyllithium; diisobutylaluminium hydride; phenylmethanethiol; triphenylphosphine; lithium hexamethyldisilazane; In tetrachloromethane; dichloromethane; toluene;
DOI:10.1016/S0960-894X(97)10067-1

Reference yield:

: 18880-00-7
1-(bromomethyl)-4-(1,1-dimethylethyl)benzene

: 172900-84-4
2(S)-tert-butoxy-carbonyl-amino-4(S)-isopropyl-5-(p-tert-butyl-phenyl)-pentanal

Guidance literature:: Multi-step reaction with 4 steps

1: 1.) LiHMDS, 2.) n-BuLi, LiAlH₄, BnSH / 1.) THF

2: NBS, PPh₃ / CH₂Cl₂

4: DIBAH / toluene

With N-Bromosuccinimide; lithium aluminium tetrahydride; n-butyllithium; diisobutylaluminium hydride; phenylmethanethiol; triphenylphosphine; lithium hexamethyldisilazane; In dichloromethane; toluene;
DOI:10.1016/S0960-894X(97)10067-1

Reference yield:

: 172900-79-7
1-bromo-2(R)-isopropyl-3-(p-tert-butyl-phenyl)-propane

: 172900-84-4
2(S)-tert-butoxy-carbonyl-amino-4(S)-isopropyl-5-(p-tert-butyl-phenyl)-pentanal

Guidance literature:: Multi-step reaction with 2 steps

2: DIBAH / toluene

With diisobutylaluminium hydride; In toluene;
DOI:10.1016/S0960-894X(97)10067-1