HYODEOXYCHOLIC ACID SODIUM SALT

Base Information

• Chemical Name: HYODEOXYCHOLIC ACID SODIUM SALT
• CAS No.: 10421-49-5
• Molecular Formula: C24H39NaO4
• Molecular Weight: 414.561
• Hs Code.: 29189900
• Mol file: 10421-49-5.mol

Synonyms:5b-Cholan-24-oic acid, 3a,6a-dihydroxy-, monosodium salt (8CI);Cholan-24-oicacid, 3,6-dihydroxy-, monosodium salt, (3a,5b,6a)- (9CI);Sodium hyodeoxycholate;Sodium hyodesoxycholate;Hyodeoxycholic acid sodium salt;

Chemical Property of HYODEOXYCHOLIC ACID SODIUM SALT

Chemical Property:

• Vapor Pressure: 2.98E-14mmHg at 25°C
• Refractive Index: 3.5 ° (C=2, H2O)
• Boiling Point: 547.1 °C at 760 mmHg
• Flash Point: 298.8 °C
• PSA: 80.59000
• LogP: 3.14320
• Water Solubility.: Sparingly soluble in water.(0.26 g/L) (25°C),

Purity/Quality:

99.90% ^*data from raw suppliers

SodiumHyodeoxycholate ^*data from reagent suppliers

Safty Information:

• Statements: 36/37/38
• Safety Statements: 26-37

MSDS Files:

SDS file from LookChem

Useful:

• Uses: It is used as pharmaceutical intermediate. Benzoylthiophenes are allosteric enhancers (AE) of agonist activity at the A1 adenosine receptor.

Technology Process of HYODEOXYCHOLIC ACID SODIUM SALT

There total 1 articles about HYODEOXYCHOLIC ACID SODIUM SALT which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

sodium hydroxide (1310-73-2) + swine bile → sodium chenodeoxycholate (2646-38-0) + 3α,6α,7α-trihydroxy-5β-cholan-24-oic acid (64898-86-8) + sodium 3α,6α-dihydroxy-5β-cholan-24-oate (10421-49-5)

Guidance literature:

swine bile; With sodium hydroxide; for 20h; Heating / reflux;

With dihydrogen peroxide; In ethyl acetate; at 70 ℃;

sodium hydroxide; With hydrogenchloride; water; more than 3 stages;

Reference yield:

sodium 3α,6α-dihydroxy-5β-cholan-24-oate (10421-49-5) → 3-hydroxy-9β-methoxy-6ξ,9α-epoxy-9,10-seco-1,3,5(10)-androstatrien-17-one (97777-66-7) + 3,9β-dihydroxy-6ξ,9α-epoxy-9,10-seco-1,3,5(10)-androstatrien-17-one (97777-65-6)

Guidance literature:

Pseudomonas putida ATCC 31752;

DOI:10.1016/S0039-128X(84)90095-3

upstream raw materials:

sodium hydroxide

Downstream raw materials:

3-hydroxy-9β-methoxy-6ξ,9α-epoxy-9,10-seco-1,3,5(10)-androstatrien-17-one

3,9β-dihydroxy-6ξ,9α-epoxy-9,10-seco-1,3,5(10)-androstatrien-17-one

Refernces