(1R,2R)-2-(Dimethylphenylsilyl)-3-diphenylphosphinoyl-1-phenylprop-1-yl tert-butyldimethylsilyl ether

Base Information

• Chemical Name: (1R,2R)-2-(Dimethylphenylsilyl)-3-diphenylphosphinoyl-1-phenylprop-1-yl tert-butyldimethylsilyl ether
• CAS No.: 191169-77-4
• Molecular Formula: C₃₅H₄₅O₂PSi₂
• Molecular Weight: 584.886
• Mol file: 191169-77-4.mol

Synonyms:(1R,2R)-2-(Dimethylphenylsilyl)-3-diphenylphosphinoyl-1-phenylprop-1-yl tert-butyldimethylsilyl ether

Chemical Property of (1R,2R)-2-(Dimethylphenylsilyl)-3-diphenylphosphinoyl-1-phenylprop-1-yl tert-butyldimethylsilyl ether

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (1R,2R)-2-(Dimethylphenylsilyl)-3-diphenylphosphinoyl-1-phenylprop-1-yl tert-butyldimethylsilyl ether

There total 2 articles about (1R,2R)-2-(Dimethylphenylsilyl)-3-diphenylphosphinoyl-1-phenylprop-1-yl tert-butyldimethylsilyl ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

dimethyl(phenyl)silyllithium (3839-31-4) + (E)-3-Diphenylphosphinoyl-1-phenylprop-2-en-1-yl tert-butyldimethylsilyl ether → (1R,2R)-2-(Dimethylphenylsilyl)-3-diphenylphosphinoyl-1-phenylprop-1-yl tert-butyldimethylsilyl ether (191169-77-4)

Guidance literature:

dimethyl(phenyl)silyllithium; With CuCN; In tetrahydrofuran; at 0 ℃; for 0.666667h;

(E)-3-Diphenylphosphinoyl-1-phenylprop-2-en-1-yl tert-butyldimethylsilyl ether; In tetrahydrofuran; at -78 - 20 ℃;

Reference yield:

(S)-(E)-3-Diphenylphosphinoyl-1-phenylprop-2-en-1-yl tert-butyldimethylsilyl ether (191169-74-1) → C35H45O2PSi2 + (1R,2R)-2-(Dimethylphenylsilyl)-3-diphenylphosphinoyl-1-phenylprop-1-yl tert-butyldimethylsilyl ether (191169-77-4)

Guidance literature:

Yield given. Title compound not separated from byproducts;

DOI:10.1016/S0040-4039(97)00658-8

upstream raw materials:

(S)-(E)-3-Diphenylphosphinoyl-1-phenylprop-2-en-1-yl tert-butyldimethylsilyl ether

dimethyl(phenyl)silyllithium