4-(5-chloro-2-methoxy-benzyl)-4-hydroxy-piperidine-1-carboxylic acid tert-butyl ester

Base Information

Chemical Name:4-(5-chloro-2-methoxy-benzyl)-4-hydroxy-piperidine-1-carboxylic acid tert-butyl ester
CAS No.:1003567-08-5
Molecular Formula:C₁₈H₂₆ClNO₄
Molecular Weight:355.862
Hs Code.:

Synonyms:4-(5-chloro-2-methoxy-benzyl)-4-hydroxy-piperidine-1-carboxylic acid tert-butyl ester

Suppliers and Price of 4-(5-chloro-2-methoxy-benzyl)-4-hydroxy-piperidine-1-carboxylic acid tert-butyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of 4-(5-chloro-2-methoxy-benzyl)-4-hydroxy-piperidine-1-carboxylic acid tert-butyl ester

Chemical Property:

Purity/Quality:: 99% ，98% ^*data from raw suppliers

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Technology Process of 4-(5-chloro-2-methoxy-benzyl)-4-hydroxy-piperidine-1-carboxylic acid tert-butyl ester

There total 2 articles about 4-(5-chloro-2-methoxy-benzyl)-4-hydroxy-piperidine-1-carboxylic acid tert-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 60633-25-2
2-bromo-4-chloroanisole

: 147804-30-6
1-oxa-6-aza-spiro-[2.5]octane-6-caboxylic acid tert-butyl ester

: 1003567-08-5
4-(5-chloro-2-methoxy-benzyl)-4-hydroxy-piperidine-1-carboxylic acid tert-butyl ester

Guidance literature:: 2-bromo-4-chloroanisole; With isopropylmagnesium chloride; In tetrahydrofuran; at 15 - 25 ℃; for 6 - 8h;

With copper(I) bromide dimethylsulfide complex; In tetrahydrofuran; at 17 - 20 ℃; for 0.166667h;

1-oxa-6-aza-spiro-[2.5]octane-6-caboxylic acid tert-butyl ester; With water; ammonium chloride; more than 3 stages;

Reference yield: 82.0%

: 147804-30-6
1-oxa-6-aza-spiro-[2.5]octane-6-caboxylic acid tert-butyl ester

: 1003567-08-5
4-(5-chloro-2-methoxy-benzyl)-4-hydroxy-piperidine-1-carboxylic acid tert-butyl ester

Guidance literature:: 2-bromo-4-chloroanisole; With isopropylmagnesium chloride; In tetrahydrofuran; at 15 - 25 ℃; for 6 - 8h;

With copper(I) bromide dimethylsulfide complex; In tetrahydrofuran; at 17 - 20 ℃; for 0.166667h;

1-oxa-6-aza-spiro-[2.5]octane-6-caboxylic acid tert-butyl ester; With water; more than 3 stages;