p-methoxyphenyl 3',4',6'-tri-O-acetyl-α-D-glucopyranose-1',2'-(3,4-di-O-benzoyl-α-L-rhamnopyranoside-2-yl)orthoacetate

Base Information

• Chemical Name: p-methoxyphenyl 3',4',6'-tri-O-acetyl-α-D-glucopyranose-1',2'-(3,4-di-O-benzoyl-α-L-rhamnopyranoside-2-yl)orthoacetate
• CAS No.: 1237532-98-7
• Molecular Formula: C₄₁H₄₄O₁₇
• Molecular Weight: 808.79
• Mol file: 1237532-98-7.mol

Synonyms:p-methoxyphenyl 3',4',6'-tri-O-acetyl-α-D-glucopyranose-1',2'-(3,4-di-O-benzoyl-α-L-rhamnopyranoside-2-yl)orthoacetate

Chemical Property of p-methoxyphenyl 3',4',6'-tri-O-acetyl-α-D-glucopyranose-1',2'-(3,4-di-O-benzoyl-α-L-rhamnopyranoside-2-yl)orthoacetate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of p-methoxyphenyl 3',4',6'-tri-O-acetyl-α-D-glucopyranose-1',2'-(3,4-di-O-benzoyl-α-L-rhamnopyranoside-2-yl)orthoacetate

There total 3 articles about p-methoxyphenyl 3',4',6'-tri-O-acetyl-α-D-glucopyranose-1',2'-(3,4-di-O-benzoyl-α-L-rhamnopyranoside-2-yl)orthoacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

p-methoxylphenyl 3,4-di-O-benzoyl-α-L-rhamnopyranoside (1124220-92-3) + 2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl trichloroacetimidate (92052-29-4) → p-methoxyphenyl 3',4',6'-tri-O-acetyl-α-D-glucopyranose-1',2'-(3,4-di-O-benzoyl-α-L-rhamnopyranoside-2-yl)orthoacetate (1237532-98-7)

Guidance literature:

With trimethylsilyl trifluoromethanesulfonate; In dichloromethane; at -10 - 20 ℃; Molecular sieve; Inert atmosphere;

DOI:10.1080/07328301003786789

Reference yield:

benzoyl chloride (98-88-4) → p-methoxyphenyl 3',4',6'-tri-O-acetyl-α-D-glucopyranose-1',2'-(3,4-di-O-benzoyl-α-L-rhamnopyranoside-2-yl)orthoacetate (1237532-98-7)

Guidance literature:

Multi-step reaction with 2 steps

1: pyridine / dichloromethane / 20 °C / Inert atmosphere; Cooling with ice

2: trimethylsilyl trifluoromethanesulfonate / dichloromethane / -10 - 20 °C / Molecular sieve; Inert atmosphere

With pyridine; trimethylsilyl trifluoromethanesulfonate; In dichloromethane;

DOI:10.1080/07328301003786789

Reference yield:

4-methoxyphenyl 4-O-benzoyl-α-L-rhamnopyranoside (583041-01-4) → p-methoxyphenyl 3',4',6'-tri-O-acetyl-α-D-glucopyranose-1',2'-(3,4-di-O-benzoyl-α-L-rhamnopyranoside-2-yl)orthoacetate (1237532-98-7)

Guidance literature:

Multi-step reaction with 2 steps

1: pyridine / dichloromethane / 20 °C / Inert atmosphere; Cooling with ice

2: trimethylsilyl trifluoromethanesulfonate / dichloromethane / -10 - 20 °C / Molecular sieve; Inert atmosphere

With pyridine; trimethylsilyl trifluoromethanesulfonate; In dichloromethane;

DOI:10.1080/07328301003786789

upstream raw materials:

p-methoxylphenyl 3,4-di-O-benzoyl-α-L-rhamnopyranoside

2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl trichloroacetimidate

benzoyl chloride

4-methoxyphenyl 4-O-benzoyl-α-L-rhamnopyranoside