5-Methyl-6-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-3,4-dihydro-2H-benzo[1,4]oxazine

Base Information

Chemical Name:5-Methyl-6-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-3,4-dihydro-2H-benzo[1,4]oxazine
CAS No.:1154740-49-4
Molecular Formula:C₁₅H₂₂BNO₃
Molecular Weight:275.156
Hs Code.:
Mol file:1154740-49-4.mol

Synonyms:5-methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydro-2H-benzo[b][1,4]oxazine

Suppliers and Price of 5-Methyl-6-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-3,4-dihydro-2H-benzo[1,4]oxazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
5-Methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydro-2H-benzo[b][1,4]oxazine 95+%
1g
$ 763.00

Chemenu
5-Methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydro-2H-benzo[b][1,4]oxazine 95%
1g
$ 724.00

Chemcia Scientific
5-Methyl-6-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-3,4-dihydro-2H-benzo[1,4]oxazine 95%
500 MG
$ 525.00

Alichem
(5-Methyl-3,4-dihydro-2h-benzo[b][1,4]oxazin-6-yl)boronicacidpinacolester
5g
$ 2685.90

Alichem
(5-Methyl-3,4-dihydro-2h-benzo[b][1,4]oxazin-6-yl)boronicacidpinacolester
1g
$ 774.86

Total 3 raw suppliers

Chemical Property of 5-Methyl-6-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-3,4-dihydro-2H-benzo[1,4]oxazine

Chemical Property:

Boiling Point:398.4±42.0 °C(Predicted)
PKA:4.37±0.20(Predicted)
Density:1.11±0.1 g/cm3(Predicted)

Purity/Quality:

97% ^*data from raw suppliers

5-Methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydro-2H-benzo[b][1,4]oxazine 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 5-Methyl-6-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-3,4-dihydro-2H-benzo[1,4]oxazine

There total 5 articles about 5-Methyl-6-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-3,4-dihydro-2H-benzo[1,4]oxazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 1154740-48-3
6-bromo-5-methyl-3,4-dihydro-2H-benzo[b][1,4]oxazine

: 73183-34-3
bis(pinacol)diborane

: 1154740-49-4
5-methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydro-2H-benzo[b][1,4]oxazine

Guidance literature:: With potassium acetate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; In N,N-dimethyl-formamide; at 90 ℃; for 5.58333h;

Reference yield:

: 4920-77-8
3-methyl-2-nitrophenol

: 1154740-49-4
5-methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydro-2H-benzo[b][1,4]oxazine

Guidance literature:: Multi-step reaction with 5 steps

1: bromine; acetic acid / 1.17 h / 0 °C / 760.05 Torr

2: platinum on activated charcoal; hydrogen / methanol / 5 h / 3102.97 Torr

3: potassium carbonate / N,N-dimethyl-formamide / 1 h / 20 °C / 760.05 Torr / Cooling with ice

4: borane-THF / tetrahydrofuran / 2.5 h / 20 °C / 760.05 Torr / Cooling with ice

5: potassium acetate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂ / N,N-dimethyl-formamide / 1 h / 90 °C / 760.05 Torr

With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; borane-THF; platinum on activated charcoal; hydrogen; bromine; potassium acetate; potassium carbonate; acetic acid; In tetrahydrofuran; methanol; N,N-dimethyl-formamide;

Reference yield:

: 85598-12-5
4-bromo-3-methyl-2-nitro-phenol

: 1154740-49-4
5-methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydro-2H-benzo[b][1,4]oxazine

Guidance literature:: Multi-step reaction with 4 steps

1: platinum on activated charcoal; hydrogen / methanol / 5 h / 3102.97 Torr

2: potassium carbonate / N,N-dimethyl-formamide / 1 h / 20 °C / 760.05 Torr / Cooling with ice

3: borane-THF / tetrahydrofuran / 2.5 h / 20 °C / 760.05 Torr / Cooling with ice

4: potassium acetate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂ / N,N-dimethyl-formamide / 1 h / 90 °C / 760.05 Torr

With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; borane-THF; platinum on activated charcoal; hydrogen; potassium acetate; potassium carbonate; In tetrahydrofuran; methanol; N,N-dimethyl-formamide;