N-[4-chloro-2-(4,4,4-trifluoro-3-methylbutyryl)-phenyl]-2,2-dimethylpropionamide

Base Information

Chemical Name:N-[4-chloro-2-(4,4,4-trifluoro-3-methylbutyryl)-phenyl]-2,2-dimethylpropionamide
CAS No.:862646-44-4
Molecular Formula:C₁₆H₁₉ClF₃NO₂
Molecular Weight:349.781
Hs Code.:

Synonyms:N-[4-chloro-2-(4,4,4-trifluoro-3-methylbutyryl)-phenyl]-2,2-dimethylpropionamide

Suppliers and Price of N-[4-chloro-2-(4,4,4-trifluoro-3-methylbutyryl)-phenyl]-2,2-dimethylpropionamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-[4-chloro-2-(4,4,4-trifluoro-3-methylbutyryl)-phenyl]-2,2-dimethylpropionamide

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Technology Process of N-[4-chloro-2-(4,4,4-trifluoro-3-methylbutyryl)-phenyl]-2,2-dimethylpropionamide

There total 2 articles about N-[4-chloro-2-(4,4,4-trifluoro-3-methylbutyryl)-phenyl]-2,2-dimethylpropionamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

: ethyl-(3-trifluoromethyl)-butyrate

: 65854-91-3
N-(4-chlorophenyl)-2,2-dimethylpropionamide

: 862646-44-4
N-[4-chloro-2-(4,4,4-trifluoro-3-methylbutyryl)-phenyl]-2,2-dimethylpropionamide

Guidance literature:: With n-butyllithium; In tetrahydrofuran; hexane; dichloromethane; cyclohexane; water;

Reference yield: 40.0%

: 6975-13-9
(+/-)-ethyl 4,4,4-trifluoro-3-methylbutanoate

: 65854-91-3
N-(4-chlorophenyl)-2,2-dimethylpropionamide

: 862646-44-4
N-[4-chloro-2-(4,4,4-trifluoro-3-methylbutyryl)-phenyl]-2,2-dimethylpropionamide

Guidance literature:: N-(4-chlorophenyl)-2,2-dimethylpropionamide; With n-butyllithium; In tetrahydrofuran; hexane; at 0 ℃; for 2h;

(+/-)-ethyl 4,4,4-trifluoro-3-methylbutanoate; In tetrahydrofuran; hexane; at -70 - 20 ℃; for 17h;

With water; In tetrahydrofuran; hexane;