n,n'-Bis(2-aminophenyl)-1,3-propanediamine

Base Information

• Chemical Name: n,n'-Bis(2-aminophenyl)-1,3-propanediamine
• CAS No.: 30381-69-2
• Molecular Formula: C₁₅H₂₀N₄
• Molecular Weight: 256.351
• European Community (EC) Number: 667-755-1
• Nikkaji Number: J668.551J
• Mol file: 30381-69-2.mol

Synonyms:n,n'-bis(2-aminophenyl)-1,3-propanediamine;SCHEMBL867417;AKOS024324570;1,3-Bis[(2-aminophenyl)amino]propane;N~1~-[3-(2-aminoanilino)propyl]-1,2-benzenediamine

Chemical Property of n,n'-Bis(2-aminophenyl)-1,3-propanediamine

Chemical Property:

• XLogP3: 2.6
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 6
• Exact Mass: 256.16879665
• Heavy Atom Count: 19
• Complexity: 222

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC=C(C(=C1)N)NCCCNC2=CC=CC=C2N

Technology Process of n,n'-Bis(2-aminophenyl)-1,3-propanediamine

There total 5 articles about n,n'-Bis(2-aminophenyl)-1,3-propanediamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N,N'-trimethylenebis(2-nitroaniline) (21708-38-3) → 1,3-bis<(o-aminophenyl)amino>propane (30381-69-2)

Guidance literature:

With hydrogen;

DOI:10.1016/S0040-4039(01)80093-9

Reference yield:

ortho-nitrofluorobenzene (1493-27-2,127723-77-7) → 1,3-bis<(o-aminophenyl)amino>propane (30381-69-2)

Guidance literature:

Multi-step reaction with 2 steps

2: H₂ / Pd/C

With hydrogen; palladium on activated charcoal;

DOI:10.1246/cl.1983.1281

Reference yield:

2-Chloronitrobenzene (88-73-3) → 1,3-bis<(o-aminophenyl)amino>propane (30381-69-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 52 percent / K₂CO₃ / 3-methyl-butan-1-ol / 24 h / Heating

2: boric acid, H₂ / 10percent Pd/C / acetic acid / 70 °C / 750.06 Torr

With hydrogen; boric acid; potassium carbonate; palladium on activated charcoal; In i-Amyl alcohol; acetic acid;

upstream raw materials:

N,N'-trimethylenebis(2-nitroaniline)

2-Chloronitrobenzene

ortho-nitrofluorobenzene