4-(2-Chloro-1,1,2-trifluoroethoxy)phenol

Base Information

Chemical Name:4-(2-Chloro-1,1,2-trifluoroethoxy)phenol
CAS No.:88553-89-3
Molecular Formula:C8H6 Cl F3 O2
Molecular Weight:226.58
Hs Code.:2909500000
DSSTox Substance ID:DTXSID00530256
Mol file:88553-89-3.mol

Synonyms:4-(2-chloro-1,1,2-trifluoroethoxy)phenol;88553-89-3;4-(2-Chloro-1,1,2-trifluoro-ethoxy)-phenol;MFCD03002308;4-(2-chloro-1,1,2-trifluoro-ethoxy)phenol;DTXSID00530256;AKOS007930352;4-(2-chloro-1,1,2-trifluoroethoxy)-phenol;A842701;4-[2-chloranyl-1,1,2-tris(fluoranyl)ethoxy]phenol

Suppliers and Price of 4-(2-Chloro-1,1,2-trifluoroethoxy)phenol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
4-(2-Chloro-1,1,2-trifluoroethoxy)phenol
25 g
$ 396.00

Crysdot
4-(2-Chloro-1,1,2-trifluoroethoxy)phenol 97%
1g
$ 711.00

CHESS?
SG000389:4-(2-Chloro-1,1,2-trifluoro-ethoxy)-phenol 98
5 g
$ 1140.00

American Custom Chemicals Corporation
4-(2-CHLORO-1,1,2-TRIFLUOROETHOXY)PHENOL 95.00%
1G
$ 1004.85

American Custom Chemicals Corporation
4-(2-CHLORO-1,1,2-TRIFLUOROETHOXY)PHENOL 95.00%
5G
$ 909.56

Total 18 raw suppliers

Chemical Property of 4-(2-Chloro-1,1,2-trifluoroethoxy)phenol

Chemical Property:

Vapor Pressure:0.00634mmHg at 25°C
Boiling Point:263.3°C at 760 mmHg
Flash Point:113.1°C
PSA：29.46000
Density:1.447g/cm³
LogP:2.89820
XLogP3:3.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:226.0008416
Heavy Atom Count:14
Complexity:183

Purity/Quality:

99%, ^*data from raw suppliers

4-(2-Chloro-1,1,2-trifluoroethoxy)phenol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Statements: 20/21/22-36/37/38
Safety Statements: 26-36/37/39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1O)OC(C(F)Cl)(F)F

Technology Process of 4-(2-Chloro-1,1,2-trifluoroethoxy)phenol

There total 2 articles about 4-(2-Chloro-1,1,2-trifluoroethoxy)phenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 403-61-2
4-(1,1,2-trifluoro-2-chloroethoxy)aniline

: 88553-89-3
4-(1,1,2-trifluoro-2-chloroethoxy)phenol

Guidance literature:: 4-(1,1,2-trifluoro-2-chloroethoxy)aniline; With sulfuric acid; sodium nitrite; In water; at -2 ℃;

With copper(II) sulfate; In water; Heating;
DOI:10.1023/B:RUJO.0000010179.88527.27

Reference yield:

: 103-90-2,8055-08-1
4-acetaminophenol

: 88553-89-3
4-(1,1,2-trifluoro-2-chloroethoxy)phenol

Guidance literature:: Multi-step reaction with 3 steps

1.1: 57 percent / KOH / acetone / 5 h / 25 °C

2.1: 71 percent / aq. HCl / ethanol / 2 h / Heating

3.1: NaNO₂; H₂SO₄ / H₂O / -2 °C

3.2: CuSO₄*9H₂O / H₂O / Heating

With hydrogenchloride; potassium hydroxide; sulfuric acid; sodium nitrite; In ethanol; water; acetone;
DOI:10.1023/B:RUJO.0000010179.88527.27