3,5-Bis(trifluoromethyl)phenyl diphenylphosphine oxide

Base Information

Chemical Name:3,5-Bis(trifluoromethyl)phenyl diphenylphosphine oxide
CAS No.:299176-62-8
Molecular Formula:C₂₀H₁₃F₆OP
Molecular Weight:414.287
Hs Code.:
DSSTox Substance ID:DTXSID40464602
Nikkaji Number:J2.177.522C
Wikidata:Q82289993
Mol file:299176-62-8.mol

Synonyms:299176-62-8;3,5-Bis(trifluoromethyl)phenyl diphenylphosphine oxide;1-diphenylphosphoryl-3,5-bis(trifluoromethyl)benzene;SCHEMBL7616716;DTXSID40464602;OLLUAZWXLAKWNC-UHFFFAOYSA-N;AKOS015911577;FT-0655407;A820109;3,5-Bis(trifluoromethyl)phenyldiphenylphosphineoxide;(3,5-Bis(trifluoromethyl)phenyl)diphenylphosphine oxide;[3,5-Bis(trifluoromethyl)phenyl](oxo)diphenyl-lambda~5~-phosphane

Suppliers and Price of 3,5-Bis(trifluoromethyl)phenyl diphenylphosphine oxide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
3,5-BIS(TRIFLUOROMETHYL)PHENYL DIPHENYLPHOSPHINE OXIDE 95.00%
5G
$ 909.56

Total 14 raw suppliers

Chemical Property of 3,5-Bis(trifluoromethyl)phenyl diphenylphosphine oxide

Chemical Property:

PSA：26.88000
LogP:5.36360
XLogP3:5.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:3
Exact Mass:414.06082100
Heavy Atom Count:28
Complexity:516

Purity/Quality:

97% ^*data from raw suppliers

3,5-BIS(TRIFLUOROMETHYL)PHENYL DIPHENYLPHOSPHINE OXIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)P(=O)(C2=CC=CC=C2)C3=CC(=CC(=C3)C(F)(F)F)C(F)(F)F

Technology Process of 3,5-Bis(trifluoromethyl)phenyl diphenylphosphine oxide

There total 5 articles about 3,5-Bis(trifluoromethyl)phenyl diphenylphosphine oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 112981-69-8
3,5-bis(trifluoromethyl)phenylmagnesium bromide

: 299176-62-8
(3,5-bis(trifluoromethyl)phenyl)diphenylphosphine oxide

Guidance literature:: With Diphenylphosphinic chloride; at 5 - 20 ℃; for 27h;

Reference yield: 40.0%

: 328-70-1
3,6-bis(trifluoromethyl)bromobenzene

: 4559-70-0
Diphenylphosphine oxide

: 299176-62-8
(3,5-bis(trifluoromethyl)phenyl)diphenylphosphine oxide

Guidance literature:: With bis(triphenylphosphine)nickel(II) chloride; 1,10-Phenanthroline; caesium carbonate; In methanol; for 12h; Inert atmosphere; Irradiation; Sealed tube;
DOI:10.1039/d1cc01858b

Reference yield:

: 328-70-1
3,6-bis(trifluoromethyl)bromobenzene

: 1499-21-4
Diphenylphosphinic chloride

: 299176-62-8
(3,5-bis(trifluoromethyl)phenyl)diphenylphosphine oxide

Guidance literature:: 3,6-bis(trifluoromethyl)bromobenzene; With iodine; magnesium; In tetrahydrofuran; at 60 ℃; for 1.5h;

Diphenylphosphinic chloride; In tetrahydrofuran; at 0 - 23 ℃; for 18h;
DOI:10.1002/chem.201703875