5-Bromo-2-((tert-butyldimethylsilyl)oxy)pyrimidine

Base Information

Chemical Name:5-Bromo-2-((tert-butyldimethylsilyl)oxy)pyrimidine
CAS No.:121519-00-4
Molecular Formula:C₁₀H₁₇BrN₂OSi
Molecular Weight:289.247
Hs Code.:2933599090
European Community (EC) Number:623-245-0
DSSTox Substance ID:DTXSID40370779
Wikidata:Q82157941
Mol file:121519-00-4.mol

Synonyms:121519-00-4;5-Bromo-2-((tert-butyldimethylsilyl)oxy)pyrimidine;5-Bromo-2-(tert-butyldimethylsilyloxy)pyrimidine;5-Bromo-2-(tert-butyldimethylsiloxy)pyrimidine;(5-bromopyrimidin-2-yl)oxy-tert-butyl-dimethylsilane;5-BROMO-2-TERT-BUTYLDIMETHYLSILYLOXY-PYRIMIDINE;5-bromo-2-[(tert-butyldimethylsilyl)oxy]pyrimidine;Pyrimidine, 5-bromo-2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-;C10H17BrN2OSi;5-BROMO-2-(T-BUTYLDIMETHYLSILYL)PYRIMIDINE;DTXSID40370779;WEA51900;MFCD01318957;AKOS015892508;AB08775;AS-76782;CS-0338653;FT-0655436;5-Bromo-2-tert-butyldimethylsilyloxypyrimidine;J-004513;5-Bromo-2-(tert-butyldimethylsiloxy)pyrimidine, 97%;5-Bromo-2-{[tert-butyl(dimethyl)silyl]oxy}pyrimidine

Suppliers and Price of 5-Bromo-2-((tert-butyldimethylsilyl)oxy)pyrimidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
5-Bromo-2-(tert-butyldimethylsiloxy)pyrimidine 97%
1g
$ 96.60

Matrix Scientific
5-Bromo-2-tert-butyldimethylsilyloxy-pyrimidine 97%
5g
$ 400.00

Matrix Scientific
5-Bromo-2-tert-butyldimethylsilyloxy-pyrimidine 97%
1g
$ 90.00

Crysdot
5-Bromo-2-((tert-butyldimethylsilyl)oxy)pyrimidine 97%
1g
$ 68.00

Crysdot
5-Bromo-2-((tert-butyldimethylsilyl)oxy)pyrimidine 97%
5g
$ 221.00

Chemenu
5-Bromo-2-tert-butyldimethylsilyloxy-pyrimidine 97%
5g
$ 209.00

American Custom Chemicals Corporation
5-BROMO-2-(TERT-BUTYLDIMETHYLSILYLOXY)PYRIMIDINE 95.00%
1G
$ 127.05

AK Scientific
5-Bromo-2-((tert-butyldimethylsilyl)oxy)pyrimidine
1g
$ 171.00

Total 38 raw suppliers

Chemical Property of 5-Bromo-2-((tert-butyldimethylsilyl)oxy)pyrimidine

Chemical Property:

Vapor Pressure:0.00257mmHg at 25°C
Refractive Index:n20/D 1.5090(lit.)
Boiling Point:296.2 °C at 760 mmHg
PKA:-0.32±0.22(Predicted)
Flash Point:132.9 °C
PSA：35.01000
Density:1.234 g/cm³
LogP:3.62310
Storage Temp.:2-8°C
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:288.02935
Heavy Atom Count:15
Complexity:210

Purity/Quality:

97% ^*data from raw suppliers

5-Bromo-2-(tert-butyldimethylsiloxy)pyrimidine 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi; Xn
Hazard Codes:Xi,Xn
Statements: 36/37/38
Safety Statements: 26-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)[Si](C)(C)OC1=NC=C(C=N1)Br
Uses 5-Bromo-2-tert-butyldimethylsilyloxy-pyrimidine (CAS# 121519-00-4) can be used to manufacture n-conjugated electrons conducting polymers.

Technology Process of 5-Bromo-2-((tert-butyldimethylsilyl)oxy)pyrimidine

There total 1 articles about 5-Bromo-2-((tert-butyldimethylsilyl)oxy)pyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 38353-06-9
5-bromo-1H-pyrimidin-2-one

: 18162-48-6
tert-butyldimethylsilyl chloride

: 121519-00-4
5-bromo-2-tert-butyldimethylsilyloxypyrimidine

Guidance literature:: With triethylamine; In dichloromethane; for 2h; Ambient temperature;

Reference yield:

: 121519-00-4
5-bromo-2-tert-butyldimethylsilyloxypyrimidine

: 121487-07-8
2-tert-butyldimethylsilyloxy-5-(α-hydroxybenzyl)pyrimidine

Guidance literature:: Multi-step reaction with 2 steps

1: butyllithium, 1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone / tetrahydrofuran; hexane / 1.5 h / -90 - -85 °C

2: 68 percent / tetrahydrofuran; hexane / 1.) -85 deg C, 30 min, 2.) 0 deg C, 20 h

With 1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone; n-butyllithium; In tetrahydrofuran; hexane;