3-NITRO-4-PYRIDINECARBOXAMIDE

Base Information

• Chemical Name: 3-NITRO-4-PYRIDINECARBOXAMIDE
• CAS No.: 59290-91-4
• Molecular Formula: C₆H₅N₃O₃
• Molecular Weight: 167.124
• Hs Code.: 2933399090
• Mol file: 59290-91-4.mol

Synonyms:3-Nitroisonicotinamide;

Chemical Property of 3-NITRO-4-PYRIDINECARBOXAMIDE

Chemical Property:

• Boiling Point: 342.7 °C at 760 mmHg
• Flash Point: 161 °C
• PSA: 101.80000
• Density: 1.476 g/cm³
• LogP: 1.31220
• Storage Temp.: 2-8°C

Purity/Quality:

98%Min ^*data from raw suppliers

3-Nitroisonicotinamide 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-NITRO-4-PYRIDINECARBOXAMIDE

There total 2 articles about 3-NITRO-4-PYRIDINECARBOXAMIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

isonicotinamide (1453-82-3) → 3-nitroisonicotinamide (59290-91-4)

Guidance literature:

isonicotinamide; With dinitrogen pentoxide; In liquid sulphur dioxide; at -38 ℃; for 0.0833333h;

With water; In liquid sulphur dioxide; at 20 ℃; for 16h;

DOI:10.1002/jhet.5570380114

Reference yield:

→ 3-nitroisonicotinamide (59290-91-4)

Guidance literature:

3-NO2-4-CO2H-Pyridin (9a), 1.) SOCl2 (fuehrt zum entspr. Saeurechlorid), 2.) H3N;

DOI:10.1021/jm00214a004

Reference yield: 98.0%

3-nitroisonicotinamide (59290-91-4) → 3-aminopyridine-4-carboxamide (64188-97-2)

Guidance literature:

With hydrogen; palladium on activated charcoal; In methanol; water; at 20 ℃; for 5h; under 3750.3 Torr;

DOI:10.1002/jhet.5570380114

upstream raw materials:

isonicotinamide

Downstream raw materials:

3-aminopyridine-4-carboxamide

3-amino-2-chloropyridine-4-carboxamide

Refernces