Technology Process of C49H51N7O12
There total 3 articles about C49H51N7O12 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
C50H55N7O11;
With
trifluoroacetic acid;
In
dichloromethane;
for 3h;
succinic acid anhydride;
With
triethylamine;
In
tetrahydrofuran;
at 37 ℃;
for 10h;
DOI:10.1021/bc2001038
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine / dichloromethane; N,N-dimethyl-formamide / 17 h
2.1: trifluoroacetic acid / dichloromethane / 3 h
2.2: 12 h / 0 - 37 °C / Inert atmosphere
3.1: trifluoroacetic acid / dichloromethane / 3 h
3.2: 10 h / 37 °C
With
O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid;
In
dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/bc2001038
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: α-chymotrypsin from bovine pancreas / dimethyl sulfoxide / aq. buffer; Enzymatic reaction
2.1: O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine / dichloromethane; N,N-dimethyl-formamide / 17 h
3.1: trifluoroacetic acid / dichloromethane / 3 h
3.2: 12 h / 0 - 37 °C / Inert atmosphere
4.1: trifluoroacetic acid / dichloromethane / 3 h
4.2: 10 h / 37 °C
With
α-chymotrypsin from bovine pancreas; O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid;
In
dichloromethane; dimethyl sulfoxide; N,N-dimethyl-formamide;
DOI:10.1021/bc2001038
