2,4-Dichloro-5-methylpyridine

Base Information

Chemical Name:2,4-Dichloro-5-methylpyridine
CAS No.:56961-78-5
Molecular Formula:C₆H₅Cl₂N
Molecular Weight:162.018
Hs Code.:2933399090
European Community (EC) Number:696-471-0
DSSTox Substance ID:DTXSID30505457
Wikidata:Q72466892

Synonyms:2,4-DICHLORO-5-METHYLPYRIDINE;56961-78-5;2,4-Dichloro-5-picoline;MFCD08704813;Pyridine, 2,4-dichloro-5-methyl-;2,4-dichloro-5-methyl-pyridine;SCHEMBL990608;AMY6209;DTXSID30505457;DUPJNQNLAKJWKU-UHFFFAOYSA-N;AKOS006288084;2,4-bis(chloranyl)-5-methyl-pyridine;AC-5730;CS-W019759;SB52538;AS-18421;SY008417;2,4-Dichloro-5-methylpyridine, AldrichCPR;FT-0649410;EN300-85525;A831262;Q-200182

Suppliers and Price of 2,4-Dichloro-5-methylpyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
2,4-Dichloro-5-picoline 95%
25 g
$ 296.00

SynQuest Laboratories
2,4-Dichloro-5-picoline 95%
5 g
$ 90.00

Matrix Scientific
2,4-Dichloro-5-picoline 95+%
5g
$ 58.00

Matrix Scientific
2,4-Dichloro-5-picoline 95+%
1g
$ 19.00

Matrix Scientific
2,4-Dichloro-5-picoline 95+%
25g
$ 198.00

Crysdot
2,4-Dichloro-5-picoline 98%
100g
$ 568.00

Biosynth Carbosynth
2,4-Dichloro-5-methylpyridine
100 g
$ 760.00

Biosynth Carbosynth
2,4-Dichloro-5-methylpyridine
250 g
$ 1050.00

Biosynth Carbosynth
2,4-Dichloro-5-methylpyridine
10 g
$ 200.00

Biosynth Carbosynth
2,4-Dichloro-5-methylpyridine
50 g
$ 500.00

Total 74 raw suppliers

Chemical Property of 2,4-Dichloro-5-methylpyridine

Chemical Property:

Vapor Pressure:0.161mmHg at 25°C
Refractive Index:1.547
Boiling Point:221.2 °C at 760 mmHg
PKA:0.38±0.10(Predicted)
Flash Point:108.6 °C
PSA：12.89000
Density:1.319g/cm³
LogP:2.69680
Storage Temp.:Inert atmosphere,Room Temperature
Water Solubility.:Slightly soluble in water.
XLogP3:2.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:160.9799046
Heavy Atom Count:9
Complexity:97.1

Purity/Quality:

99%, ^*data from raw suppliers

2,4-Dichloro-5-picoline 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn
Statements: 22

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CN=C(C=C1Cl)Cl
Uses 2,4-Dichloro-5-methylpyridine is used as pharmaceutical intermediates.

Technology Process of 2,4-Dichloro-5-methylpyridine

There total 3 articles about 2,4-Dichloro-5-methylpyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 20173-49-3
2-chloro-5-methylpyridine-N-oxide

: 58584-94-4
2,6-dichloro-3-methylpyridine

: 56961-78-5
2,4-dichloro-5-methylpyridine

Guidance literature:: With triethylamine; trichlorophosphate; In dichloromethane; at 0 - 20 ℃; for 26h;

Reference yield:

: 18368-64-4
2-chloro-5-methylpyridine

: 58584-94-4
2,6-dichloro-3-methylpyridine

: 56961-78-5
2,4-dichloro-5-methylpyridine

Guidance literature:: Multi-step reaction with 2 steps

1.1: urea hydrogen peroxide adduct; trifluoroacetic acid / dichloromethane / 1.75 h / 0 - 20 °C

1.2: 0.25 h

2.1: triethylamine; trichlorophosphate / dichloromethane / 3.58 h / -10 - 20 °C / Heating / reflux

With urea hydrogen peroxide adduct; triethylamine; trifluoroacetic acid; trichlorophosphate; In dichloromethane;