C₅₉H₁₀₂O₁₂Si₂

Base Information

• Chemical Name: C₅₉H₁₀₂O₁₂Si₂
• CAS No.: 175612-36-9
• Molecular Formula: C₅₉H₁₀₂O₁₂Si₂
• Molecular Weight: 1059.62
• Mol file: 175612-36-9.mol

Synonyms:C₅₉H₁₀₂O₁₂Si₂

Chemical Property of C₅₉H₁₀₂O₁₂Si₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₅₉H₁₀₂O₁₂Si₂

There total 47 articles about C₅₉H₁₀₂O₁₂Si₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.5%

C60H104O12Si2 (175612-35-8) → C59H102O12Si2 (175612-36-9)

Guidance literature:

With sodium hydroxide; In tetrahydrofuran; methanol; for 6h; Ambient temperature;

Reference yield:

(S)-1-(1-Ethylpropylidenamino)-2-methoxymethylpyrrolidin (59983-36-7) → C59H102O12Si2 (175612-36-9)

Guidance literature:

Multi-step reaction with 17 steps

1: 1.) LDA / 1.) Et₂O, hexane, 0 deg C, 4 h, 2.) Et₂O, hexane, from -110 deg C to RT, 12 h

2: 97 percent / O₃ / CH₂Cl₂ / -78 °C

3: 1.) TiCl₄, Et₃N / 1.) CH₂Cl₂, -78 deg C, 2.5 h, 2.) CH₂Cl₂, -78 deg C, 2.5 h

4: 89 percent / SmI₂ / tetrahydrofuran / 1 h / -10 °C

5: 86 percent / 2,6-lutidine / CH₂Cl₂ / 1 h / 0 - 20 °C

6: 99 percent / H₂ / 10percent Pd/C / ethanol / 48 h / Ambient temperature

7: Et₃N, SOCl₂ / CH₂Cl₂ / 0.17 h / 0 °C

8: RuCl₃, NaIO₄ / CCl₄; acetonitrile; H₂O / 1.5 h / 0 °C

9: 1.) t-BuLi, HMPA, 3.) 30percent aq. H₂SO₄

10: 91 percent / NBS, AgClO₄ / acetone; H₂O / 0.01 h / 0 °C

11: 1.) n-Bu₃B, air, 2.) NaBH₄, 3.) 30percent aq. H₂O₂, 2.5M aq. NaOH

12: 93 percent / CSA / CH₂Cl₂ / 3 h / 0 °C

13: 97 percent / Dibal-H / CH₂Cl₂; toluene / 4 h / -78 °C

14: 85 percent / HF*pyridine / CH₂Cl₂ / 1.5 h / 0 °C

15: 95 percent / MnO₂ / CH₂Cl₂ / 4 h / Ambient temperature

16: 1.) BuLi / 1.) THF, hexane, 0 deg C, 15 min, 2.) THF, hexane, from 0 deg C to RT, 18 h

17: 91.5 percent / aq. NaOH / methanol; tetrahydrofuran / 6 h / Ambient temperature

With 2,6-dimethylpyridine; N,N,N,N,N,N-hexamethylphosphoric triamide; manganese(IV) oxide; ruthenium trichloride; sodium hydroxide; sodium tetrahydroborate; sodium periodate; N-Bromosuccinimide; n-butyllithium; thionyl chloride; samarium diiodide; air; tributyl borane; sulfuric acid; camphor-10-sulfonic acid; hydrogen; dihydrogen peroxide; tert.-butyl lithium; silver perchlorate; titanium tetrachloride; diisobutylaluminium hydride; pyridine hydrogenfluoride; ozone; triethylamine; lithium diisopropyl amide; palladium on activated charcoal; In tetrahydrofuran; methanol; tetrachloromethane; ethanol; dichloromethane; water; acetone; toluene; acetonitrile;

Reference yield:

L-rhamnose (73-34-7) → C59H102O12Si2 (175612-36-9)

Guidance literature:

Multi-step reaction with 25 steps

1: 91 percent / 4-DMAP, Et₃N / CH₂Cl₂ / 1 h / 0 °C

2: 81 percent / BF₃*Et₂O, TMSOTf / acetonitrile / 3 h / 0 °C

3: 100 percent / MeONa / methanol / 24 h / 25 °C

4: 1.) n-Bu₂SnO, 2.) CsF / 1.) MeOH, reflux, 4 h, 2.) DMF, 40 deg C, 16 h

5: 1.) imidazole, NaH

6: 60 percent / n-Bu₃SnH, AIBN / toluene / 1 h / 110 °C

7: 1.) O₃, 2.) NaBH₄ / 1.) CH₂Cl₂, MeOH, -78 deg C, 20 min, 2.) CH₂Cl₂, MeOH, from -78 deg C to RT, 7 h

8: 83 percent / Ph₃P, I₂, imidazole / CH₂Cl₂ / 2 h / 40 °C

9: 1.) LDA / 1.) Et₂O, hexane, 0 deg C, 4 h, 2.) Et₂O, hexane, from -110 deg C to RT, 12 h

10: 97 percent / O₃ / CH₂Cl₂ / -78 °C

11: 1.) TiCl₄, Et₃N / 1.) CH₂Cl₂, -78 deg C, 2.5 h, 2.) CH₂Cl₂, -78 deg C, 2.5 h

12: 89 percent / SmI₂ / tetrahydrofuran / 1 h / -10 °C

13: 86 percent / 2,6-lutidine / CH₂Cl₂ / 1 h / 0 - 20 °C

14: 99 percent / H₂ / 10percent Pd/C / ethanol / 48 h / Ambient temperature

15: Et₃N, SOCl₂ / CH₂Cl₂ / 0.17 h / 0 °C

16: RuCl₃, NaIO₄ / CCl₄; acetonitrile; H₂O / 1.5 h / 0 °C

17: 1.) t-BuLi, HMPA, 3.) 30percent aq. H₂SO₄

18: 91 percent / NBS, AgClO₄ / acetone; H₂O / 0.01 h / 0 °C

19: 1.) n-Bu₃B, air, 2.) NaBH₄, 3.) 30percent aq. H₂O₂, 2.5M aq. NaOH

20: 93 percent / CSA / CH₂Cl₂ / 3 h / 0 °C

21: 97 percent / Dibal-H / CH₂Cl₂; toluene / 4 h / -78 °C

22: 85 percent / HF*pyridine / CH₂Cl₂ / 1.5 h / 0 °C

23: 95 percent / MnO₂ / CH₂Cl₂ / 4 h / Ambient temperature

24: 1.) BuLi / 1.) THF, hexane, 0 deg C, 15 min, 2.) THF, hexane, from 0 deg C to RT, 18 h

25: 91.5 percent / aq. NaOH / methanol; tetrahydrofuran / 6 h / Ambient temperature

With 1H-imidazole; 2,6-dimethylpyridine; N,N,N,N,N,N-hexamethylphosphoric triamide; dmap; manganese(IV) oxide; ruthenium trichloride; sodium hydroxide; sodium tetrahydroborate; sodium periodate; N-Bromosuccinimide; n-butyllithium; thionyl chloride; samarium diiodide; air; 2,2'-azobis(isobutyronitrile); tributyl borane; trimethylsilyl trifluoromethanesulfonate; sulfuric acid; camphor-10-sulfonic acid; boron trifluoride diethyl etherate; hydrogen; dihydrogen peroxide; iodine; tert.-butyl lithium; tri-n-butyl-tin hydride; sodium methylate; silver perchlorate; titanium tetrachloride; sodium hydride; diisobutylaluminium hydride; di(n-butyl)tin oxide; pyridine hydrogenfluoride; ozone; triethylamine; triphenylphosphine; cesium fluoride; lithium diisopropyl amide; palladium on activated charcoal; In tetrahydrofuran; methanol; tetrachloromethane; ethanol; dichloromethane; water; acetone; toluene; acetonitrile;

upstream raw materials:

C₆₀H₁₀₄O₁₂Si₂

(S)-1-(1-Ethylpropylidenamino)-2-methoxymethylpyrrolidin

L-rhamnose

1,2,3,4-tetra-O-acetyl-L-rhamnopyranose

Downstream raw materials:

C₅₉H₁₀₀O₁₁Si₂