13-(4-hydroxyphenyl)-3, 3-dimethyl-3,4-dihydro-1H-indazolo[1,2-b]phthalazine-1,6,11(2H, 13H)-trione

Base Information

• Chemical Name: 13-(4-hydroxyphenyl)-3, 3-dimethyl-3,4-dihydro-1H-indazolo[1,2-b]phthalazine-1,6,11(2H, 13H)-trione
• CAS No.: 1384973-99-2
• Molecular Formula: C₂₃H₂₀N₂O₄
• Molecular Weight: 388.423
• Mol file: 1384973-99-2.mol

Synonyms:13-(4-hydroxyphenyl)-3, 3-dimethyl-3,4-dihydro-1H-indazolo[1,2-b]phthalazine-1,6,11(2H, 13H)-trione

Chemical Property of 13-(4-hydroxyphenyl)-3, 3-dimethyl-3,4-dihydro-1H-indazolo[1,2-b]phthalazine-1,6,11(2H, 13H)-trione

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of 13-(4-hydroxyphenyl)-3, 3-dimethyl-3,4-dihydro-1H-indazolo[1,2-b]phthalazine-1,6,11(2H, 13H)-trione

There total 4 articles about 13-(4-hydroxyphenyl)-3, 3-dimethyl-3,4-dihydro-1H-indazolo[1,2-b]phthalazine-1,6,11(2H, 13H)-trione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

phthalic anhydride (85-44-9) + 4-hydroxy-benzaldehyde (123-08-0,65581-83-1) + dimedone (126-81-8) → 13-(4-hydroxyphenyl)-3, 3-dimethyl-3,4-dihydro-1H-indazolo[1,2-b]phthalazine-1,6,11(2H, 13H)-trione (1384973-99-2)

Guidance literature:

With hydrazine hydrate; In neat (no solvent); at 80 ℃; for 0.216667h; Green chemistry;

DOI:10.1002/jhet.3989

Reference yield: 92.0%

2,3-dihydrophthalazine-1,4-dione (1445-69-8) + 4-hydroxy-benzaldehyde (123-08-0,65581-83-1) + dimedone (126-81-8) → 13-(4-hydroxyphenyl)-3, 3-dimethyl-3,4-dihydro-1H-indazolo[1,2-b]phthalazine-1,6,11(2H, 13H)-trione (1384973-99-2)

Guidance literature:

With KHSO₄-SiO₂; In neat (no solvent); at 80 ℃; for 0.166667h;

Reference yield: 88.0%

phthaloyldihydrazine (3645-45-2) + 4-hydroxy-benzaldehyde (123-08-0,65581-83-1) + dimedone (126-81-8) → 13-(4-hydroxyphenyl)-3, 3-dimethyl-3,4-dihydro-1H-indazolo[1,2-b]phthalazine-1,6,11(2H, 13H)-trione (1384973-99-2)

Guidance literature:

With phosphotungstic acid supported on 1,4-phenylenediamine-modified silica-coated manganese ferrite with H₃PW₁₂O₄₀ nanoparticles; In neat (no solvent); at 80 ℃; for 0.5h; Solvent;

DOI:10.1016/j.poly.2019.01.065

upstream raw materials:

2,3-dihydrophthalazine-1,4-dione

4-hydroxy-benzaldehyde

dimedone

phthalimide