N¹,N²-dibenzyloxycarbonyl-N²-tert-butoxycarbonyl-N¹-ethyl-1,2-ethylenediamine

Base Information

• Chemical Name: N¹,N²-dibenzyloxycarbonyl-N²-tert-butoxycarbonyl-N¹-ethyl-1,2-ethylenediamine
• CAS No.: 113283-91-3
• Molecular Formula: C₂₅H₃₂N₂O₆
• Molecular Weight: 456.539
• Mol file: 113283-91-3.mol

Synonyms:N¹,N²-dibenzyloxycarbonyl-N²-tert-butoxycarbonyl-N¹-ethyl-1,2-ethylenediamine

Chemical Property of N¹,N²-dibenzyloxycarbonyl-N²-tert-butoxycarbonyl-N¹-ethyl-1,2-ethylenediamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N¹,N²-dibenzyloxycarbonyl-N²-tert-butoxycarbonyl-N¹-ethyl-1,2-ethylenediamine

There total 6 articles about N¹,N²-dibenzyloxycarbonyl-N²-tert-butoxycarbonyl-N¹-ethyl-1,2-ethylenediamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

di-tert-butyl dicarbonate (24424-99-5) + N1-ethyl-N1,N2-Z2-ethylenediamine (113283-89-9) → N1,N2-dibenzyloxycarbonyl-N2-tert-butoxycarbonyl-N1-ethyl-1,2-ethylenediamine (113283-91-3)

Guidance literature:

With dmap; In acetonitrile; for 5h; Ambient temperature;

Reference yield: 79.0%

benzyl N-ethyl N-(2-hydroxyethyl) carbamate (67249-24-5) + benzyl N-[(tert-butoxy)carbonyl]carbamate (120542-13-4) → N1,N2-dibenzyloxycarbonyl-N2-tert-butoxycarbonyl-N1-ethyl-1,2-ethylenediamine (113283-91-3)

Guidance literature:

With triphenylphosphine; diethylazodicarboxylate; In acetonitrile; for 20h; Ambient temperature;

Reference yield:

benzyl chloroformate (501-53-1,94274-21-2) → N1,N2-dibenzyloxycarbonyl-N2-tert-butoxycarbonyl-N1-ethyl-1,2-ethylenediamine (113283-91-3)

Guidance literature:

Multi-step reaction with 2 steps

1: aq. Na₂CO₃

2: DMAP / acetonitrile / 15 h / Ambient temperature

With dmap; sodium carbonate; In acetonitrile;

upstream raw materials:

di-tert-butyl dicarbonate

N¹-ethyl-N¹,N²-Z₂-ethylenediamine

benzyl N-ethyl N-(2-hydroxyethyl) carbamate

benzyl N-[(tert-butoxy)carbonyl]carbamate

Downstream raw materials:

N¹-tert-butoxycarbonyl-N²-ethylethane-1,2-diamine

N²-Boc-N¹-ethyl-N¹-Z-ethylenediamine