4-methoxycarbonyl-2-(1-pyrrolidinylmethyl)-1-[(3,4-dichlorophenyl)acetyl]-piperidine

Base Information

Chemical Name:4-methoxycarbonyl-2-(1-pyrrolidinylmethyl)-1-[(3,4-dichlorophenyl)acetyl]-piperidine
CAS No.:261904-04-5
Molecular Formula:C₁₉H₂₅Cl₂N₃O₃
Molecular Weight:413.321
Hs Code.:

Synonyms:4-methoxycarbonyl-2-(1-pyrrolidinylmethyl)-1-[(3,4-dichlorophenyl)acetyl]-piperidine

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Chemical Property of 4-methoxycarbonyl-2-(1-pyrrolidinylmethyl)-1-[(3,4-dichlorophenyl)acetyl]-piperidine

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Technology Process of 4-methoxycarbonyl-2-(1-pyrrolidinylmethyl)-1-[(3,4-dichlorophenyl)acetyl]-piperidine

There total 2 articles about 4-methoxycarbonyl-2-(1-pyrrolidinylmethyl)-1-[(3,4-dichlorophenyl)acetyl]-piperidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 124-38-9,18923-20-1
carbon dioxide

: 126766-48-1
1-[(3,4-dichlorophenyl)acetyl]-2-(R)-[(1-pyrrolidinyl)methyl] piperazine

: 145577-00-0
[11C]methyl triflate

: 261904-04-5
4-methoxycarbonyl-2-(1-pyrrolidinylmethyl)-1-[(3,4-dichlorophenyl)acetyl]-piperidine

Guidance literature:: carbon dioxide; 1-[(3,4-dichlorophenyl)acetyl]-2-(R)-[(1-pyrrolidinyl)methyl] piperazine; With tetrabutylammonium trifluoromethylsulfonate; caesium carbonate; In N,N-dimethyl-formamide; for 1h;

[11C]methyl triflate; In N,N-dimethyl-formamide; at 20 - 25 ℃; for 0.0333333 - 0.0833333h; Product distribution / selectivity;

Reference yield: 34.0%

: 54245-42-0
[11C]methyl iodide

: 124-38-9,18923-20-1
carbon dioxide

: 126766-48-1
1-[(3,4-dichlorophenyl)acetyl]-2-(R)-[(1-pyrrolidinyl)methyl] piperazine

: 261904-04-5
4-methoxycarbonyl-2-(1-pyrrolidinylmethyl)-1-[(3,4-dichlorophenyl)acetyl]-piperidine

Guidance literature:: carbon dioxide; 1-[(3,4-dichlorophenyl)acetyl]-2-(R)-[(1-pyrrolidinyl)methyl] piperazine; With tetrabutylammonium trifluoromethylsulfonate; caesium carbonate; In N,N-dimethyl-formamide; for 1h;

[11C]methyl iodide; In N,N-dimethyl-formamide; at 25 ℃; for 0.0833333h; Product distribution / selectivity;