6-fluoro-2-(4-(5-(4-fluoro-3-methoxyphenyl)-1H-imidazol-1-yl)phenyl)benzo[d]thiazole

Base Information

Chemical Name:6-fluoro-2-(4-(5-(4-fluoro-3-methoxyphenyl)-1H-imidazol-1-yl)phenyl)benzo[d]thiazole
CAS No.:1393815-45-6
Molecular Formula:C₂₃H₁₅F₂N₃OS
Molecular Weight:419.454
Hs Code.:

Synonyms:6-fluoro-2-(4-(5-(4-fluoro-3-methoxyphenyl)-1H-imidazol-1-yl)phenyl)benzo[d]thiazole

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Chemical Property of 6-fluoro-2-(4-(5-(4-fluoro-3-methoxyphenyl)-1H-imidazol-1-yl)phenyl)benzo[d]thiazole

Chemical Property:

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Technology Process of 6-fluoro-2-(4-(5-(4-fluoro-3-methoxyphenyl)-1H-imidazol-1-yl)phenyl)benzo[d]thiazole

There total 7 articles about 6-fluoro-2-(4-(5-(4-fluoro-3-methoxyphenyl)-1H-imidazol-1-yl)phenyl)benzo[d]thiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1393816-17-5
C₂₁H₁₄F₂N₂OS

: 38622-91-2,36635-61-7
[(p-methylphenyl)sulfonylmethyl]isonitrile

: 1393815-45-6
6-fluoro-2-(4-(5-(4-fluoro-3-methoxyphenyl)-1H-imidazol-1-yl)phenyl)benzo[d]thiazole

Guidance literature:: With potassium carbonate; In methanol; 1,2-dimethoxyethane; for 12h; Reflux;

Reference yield:

: 347-81-9
4-nitro-N-(4-fluorophenyl)benzamide

: 1393815-45-6
6-fluoro-2-(4-(5-(4-fluoro-3-methoxyphenyl)-1H-imidazol-1-yl)phenyl)benzo[d]thiazole

Guidance literature:: Multi-step reaction with 5 steps

1: Lawessons reagent / toluene / 7 h / 110 °C

2: potassium hexacyanoferrate(III); sodium hydroxide / water / 3 h / 90 °C

3: tin(II) chloride dihdyrate / ethanol / 2 h / 80 °C

4: acetic acid / ethanol / 2 h / Reflux

5: potassium carbonate / 1,2-dimethoxyethane; methanol / 12 h / Reflux

With Lawessons reagent; tin(II) chloride dihdyrate; potassium carbonate; sodium hydroxide; potassium hexacyanoferrate(III); acetic acid; In methanol; 1,2-dimethoxyethane; ethanol; water; toluene;

Reference yield:

: 122-04-3
4-nitro-benzoyl chloride

: 1393815-45-6
6-fluoro-2-(4-(5-(4-fluoro-3-methoxyphenyl)-1H-imidazol-1-yl)phenyl)benzo[d]thiazole

Guidance literature:: Multi-step reaction with 6 steps

1: pyridine / 2 h / Reflux

2: Lawessons reagent / toluene / 7 h / 110 °C

3: potassium hexacyanoferrate(III); sodium hydroxide / water / 3 h / 90 °C

4: tin(II) chloride dihdyrate / ethanol / 2 h / 80 °C

5: acetic acid / ethanol / 2 h / Reflux

6: potassium carbonate / 1,2-dimethoxyethane; methanol / 12 h / Reflux

With Lawessons reagent; pyridine; tin(II) chloride dihdyrate; potassium carbonate; sodium hydroxide; potassium hexacyanoferrate(III); acetic acid; In methanol; 1,2-dimethoxyethane; ethanol; water; toluene;