4-(4-fluorophenyl)-3-[4-(methylsulfonyl)phenyl]-5-(trifluoromethyl)-1H-pyrazole

Base Information

Chemical Name:4-(4-fluorophenyl)-3-[4-(methylsulfonyl)phenyl]-5-(trifluoromethyl)-1H-pyrazole
CAS No.:175676-90-1
Molecular Formula:C₁₇H₁₂F₄N₂O₂S
Molecular Weight:384.354
Hs Code.:

Synonyms:4-(4-fluorophenyl)-3-[4-(methylsulfonyl)phenyl]-5-(trifluoromethyl)-1H-pyrazole

Suppliers and Price of 4-(4-fluorophenyl)-3-[4-(methylsulfonyl)phenyl]-5-(trifluoromethyl)-1H-pyrazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4-(4-fluorophenyl)-3-[4-(methylsulfonyl)phenyl]-5-(trifluoromethyl)-1H-pyrazole

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-(4-fluorophenyl)-3-[4-(methylsulfonyl)phenyl]-5-(trifluoromethyl)-1H-pyrazole

There total 6 articles about 4-(4-fluorophenyl)-3-[4-(methylsulfonyl)phenyl]-5-(trifluoromethyl)-1H-pyrazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

Oxone: Oxone

: 175676-89-8
4-(4-fluorophenyl)-3-[4-(methylthio)phenyl]-5-(trifluoromethyl)-1H-pyrazole

: 175676-90-1
4-(4-fluorophenyl)-3-[4-(methylsulfonyl)phenyl]-5-(trifluoromethyl)-1H-pyrazole

Guidance literature:: In methanol; water;

Reference yield:

: 175676-89-8
4-(4-fluorophenyl)-3-[4-(methylthio)phenyl]-5-(trifluoromethyl)-1H-pyrazole

: 175676-90-1
4-(4-fluorophenyl)-3-[4-(methylsulfonyl)phenyl]-5-(trifluoromethyl)-1H-pyrazole

Guidance literature:: With Oxone; In methanol; water; Yield given;
DOI:10.1016/S0960-894X(97)00372-7

Reference yield:

: 100-68-5
methyl-phenyl-thioether

: 175676-90-1
4-(4-fluorophenyl)-3-[4-(methylsulfonyl)phenyl]-5-(trifluoromethyl)-1H-pyrazole

Guidance literature:: Multi-step reaction with 4 steps

1: 63 percent / PPA / 120 °C

2: 1.) LiHMDS / 1.) THF, -78 deg C, 2.) -78 deg C -> 0 deg C

3: N₂H₄ / acetic acid / Heating

4: Oxone / methanol; H₂O

With Oxone; lithium hexamethyldisilazane; hydrazine; In methanol; water; acetic acid;
DOI:10.1016/S0960-894X(97)00372-7