Technology Process of C20H13BrF3N5O3
There total 4 articles about C20H13BrF3N5O3 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
sodium hydride;
In
tetrahydrofuran; mineral oil;
at 20 - 80 ℃;
for 3h;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: potassium carbonate / N,N-dimethyl-formamide / 16 h / 90 °C
2: sodium hydrogencarbonate / tetrakis(triphenylphosphine) palladium(0) / N,N-dimethyl-formamide / 0.33 h / 140 °C / Microwave irradiation
3: sodium hydride / tetrahydrofuran; mineral oil / 3 h / 20 - 80 °C
With
sodium hydride; sodium hydrogencarbonate; potassium carbonate;
tetrakis(triphenylphosphine) palladium(0);
In
tetrahydrofuran; N,N-dimethyl-formamide; mineral oil;
2: Suzuki Coupling;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: sodium hydrogencarbonate / tetrakis(triphenylphosphine) palladium(0) / N,N-dimethyl-formamide / 0.33 h / 140 °C / Microwave irradiation
2: sodium hydride / tetrahydrofuran; mineral oil / 3 h / 20 - 80 °C
With
sodium hydride; sodium hydrogencarbonate;
tetrakis(triphenylphosphine) palladium(0);
In
tetrahydrofuran; N,N-dimethyl-formamide; mineral oil;
1: Suzuki Coupling;