octan-5,7-dienoic acid

Base Information

• Chemical Name: octan-5,7-dienoic acid
• CAS No.: 109387-87-3
• Molecular Formula: C₈H₁₂O₂
• Molecular Weight: 140.182
• Mol file: 109387-87-3.mol

Synonyms:octan-5,7-dienoic acid

Chemical Property of octan-5,7-dienoic acid

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of octan-5,7-dienoic acid

There total 2 articles about octan-5,7-dienoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(E)-8-hydroxyoct-6-enoic acid → 7-formylheptanoic acid (929-48-6) + octan-5,7-dienoic acid (109387-87-3) + (E)-octa-5,7-dienoic acid (154019-74-6)

Guidance literature:

With C₂₅H₂₁ClNO₂Ru⁽¹⁺⁾*F₆P^(1-); In dichloromethane; N,N-dimethyl acetamide; at 100 ℃; for 1h; Overall yield = 77 %; Overall yield = 134 mg; enantioselective reaction; Sealed tube; Schlenk technique;

DOI:10.1021/jacs.5b05786

Reference yield:

(E)-5-(6-hydroxyhex-4-en-1-yl)-2,2-dimethyl-1,3-dioxane-4,6-dione (1311201-38-3) → 7-formylheptanoic acid (929-48-6) + octan-5,7-dienoic acid (109387-87-3) + (E)-octa-5,7-dienoic acid (154019-74-6)

Guidance literature:

Multi-step reaction with 2 steps

1: pyridine / water / 3 h / 100 °C

2: C₂₅H₂₁ClNO₂Ru⁽¹⁺⁾*F₆P^(1-) / dichloromethane; N,N-dimethyl acetamide / 1 h / 100 °C / Sealed tube; Schlenk technique

With pyridine; C₂₅H₂₁ClNO₂Ru⁽¹⁺⁾*F₆P^(1-); In dichloromethane; N,N-dimethyl acetamide; water;

DOI:10.1021/jacs.5b05786

Reference yield: 95.0%

Phenylselenyl chloride (5707-04-0) + octan-5,7-dienoic acid (109387-87-3) → 6-((E)-3-Phenylselanyl-propenyl)-tetrahydro-pyran-2-one (109387-75-9)

Guidance literature:

With triethylamine; In dichloromethane; at -78 ℃; dark;

DOI:10.1016/S0040-4039(00)85362-9

upstream raw materials:

(E)-5-(6-hydroxyhex-4-en-1-yl)-2,2-dimethyl-1,3-dioxane-4,6-dione

Downstream raw materials:

6-((E)-3-Phenylselanyl-propenyl)-tetrahydro-pyran-2-one

6-((E)-3-Phenylsulfanyl-propenyl)-tetrahydro-pyran-2-one