4-{3-[2-(4-Chlorophenylsulfanyl)benzyl]-4,4-dimethyl-2,5-dioxoimidazolidin-1-yl}-2-trifluoromethylbenzonitrile

Base Information

Chemical Name:4-{3-[2-(4-Chlorophenylsulfanyl)benzyl]-4,4-dimethyl-2,5-dioxoimidazolidin-1-yl}-2-trifluoromethylbenzonitrile
CAS No.:1181080-14-7
Molecular Formula:C₂₆H₁₉ClF₃N₃O₂S
Molecular Weight:529.97
Hs Code.:

Synonyms:4-{3-[2-(4-Chlorophenylsulfanyl)benzyl]-4,4-dimethyl-2,5-dioxoimidazolidin-1-yl}-2-trifluoromethylbenzonitrile

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Chemical Property of 4-{3-[2-(4-Chlorophenylsulfanyl)benzyl]-4,4-dimethyl-2,5-dioxoimidazolidin-1-yl}-2-trifluoromethylbenzonitrile

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Technology Process of 4-{3-[2-(4-Chlorophenylsulfanyl)benzyl]-4,4-dimethyl-2,5-dioxoimidazolidin-1-yl}-2-trifluoromethylbenzonitrile

There total 2 articles about 4-{3-[2-(4-Chlorophenylsulfanyl)benzyl]-4,4-dimethyl-2,5-dioxoimidazolidin-1-yl}-2-trifluoromethylbenzonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 41932-37-0
2-(4-chlorophenylsulfanyl)benzyl bromide

: 143782-20-1
4-(4,4-dimethyl-2,5-dioxoimidazolidin-1-yl)-2-(trifluoromethyl)benzonitrile

: 1181080-14-7
4-{3-[2-(4-Chlorophenylsulfanyl)benzyl]-4,4-dimethyl-2,5-dioxoimidazolidin-1-yl}-2-trifluoromethylbenzonitrile

Guidance literature:: With caesium carbonate; In acetonitrile; at 20 ℃; for 4h;

Reference yield:

: 13459-59-1
(2-(4-chlorophenylthio)phenyl)methanol

: 1181080-14-7
4-{3-[2-(4-Chlorophenylsulfanyl)benzyl]-4,4-dimethyl-2,5-dioxoimidazolidin-1-yl}-2-trifluoromethylbenzonitrile

Guidance literature:: Multi-step reaction with 2 steps

1: 1H-imidazole; triphenylphosphine; bromine / dichloromethane / 48.17 h / 5 - 20 °C

2: caesium carbonate / acetonitrile / 4 h / 20 °C

With 1H-imidazole; bromine; caesium carbonate; triphenylphosphine; In dichloromethane; acetonitrile;