methyl 4,6-O-benzylidene-3-C-<(Z)-2-hydroxyethylidene>-2,2¹-O-isopropylidene-α-D-ribo-hexopyranoside

Base Information

• Chemical Name: methyl 4,6-O-benzylidene-3-C-<(Z)-2-hydroxyethylidene>-2,2¹-O-isopropylidene-α-D-ribo-hexopyranoside
• CAS No.: 110889-27-5
• Molecular Formula: C₁₉H₂₄O₆
• Molecular Weight: 348.396

Synonyms:methyl 4,6-O-benzylidene-3-C-<(Z)-2-hydroxyethylidene>-2,2¹-O-isopropylidene-α-D-ribo-hexopyranoside

Chemical Property of methyl 4,6-O-benzylidene-3-C-<(Z)-2-hydroxyethylidene>-2,2¹-O-isopropylidene-α-D-ribo-hexopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 4,6-O-benzylidene-3-C-<(Z)-2-hydroxyethylidene>-2,2¹-O-isopropylidene-α-D-ribo-hexopyranoside

There total 1 articles about methyl 4,6-O-benzylidene-3-C-<(Z)-2-hydroxyethylidene>-2,2¹-O-isopropylidene-α-D-ribo-hexopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

2-Methoxypropene (116-11-0) + (4aR,6S,7R,8aS)-8-[2-Hydroxy-eth-(E)-ylidene]-6-methoxy-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-7-ol (110889-24-2) → methyl 4,6-O-benzylidene-3-C-<(Z)-2-hydroxyethylidene>-2,21-O-isopropylidene-α-D-ribo-hexopyranoside (110889-27-5)

Guidance literature:

With pyridinium p-toluenesulfonate; In N,N-dimethyl-formamide; Ambient temperature;

DOI:10.1016/S0008-6215(00)90006-5

Reference yield: 62.0%

methyl 4,6-O-benzylidene-3-C-<(Z)-2-hydroxyethylidene>-2,21-O-isopropylidene-α-D-ribo-hexopyranoside (110889-27-5) → methyl 4,6-O-benzylidene-3-C-<(R)-1,2-dihydroxyethyl>-2,21-O-isopropylidene-α-D-glucopyranoside (110889-28-6,110889-29-7)

Guidance literature:

With osmium(VIII) oxide; water; 4-methylmorpholine N-oxide; In tetrahydrofuran; tert-butyl alcohol; Ambient temperature;

DOI:10.1016/S0008-6215(00)90006-5

Reference yield:

methyl 4,6-O-benzylidene-3-C-<(Z)-2-hydroxyethylidene>-2,21-O-isopropylidene-α-D-ribo-hexopyranoside (110889-27-5) → methyl 11-O-acetyl-3-C-<(S)-1,2-dihydroxyethyl>-2,21-O-isopropylidene-6-O-pivaloyl-4-O-p-tolylsulfonyl-α-D-glucopyranoside (110889-33-3)

Guidance literature:

Multi-step reaction with 7 steps

1: 62 percent / osmium tetraoxide, 4-methylmorpholine N-oxide, water / 2-methyl-propan-2-ol; tetrahydrofuran / Ambient temperature

2: dimethyl sulfoxide, oxalyl chloride, triethylamine / 2-methyl-propan-2-ol; CH₂Cl₂; H₂O / 1 h, room temperature

3: sodium borohydride / methanol / 1 h

4: pyridine

5: hydrogen, acetic acid / palladium hydroxide on charcoal / ethanol / 44 h / Ambient temperature

6: 87 percent / pyridine / 24 h / 60 °C

7: 20 percent / 4-dimethylaminopyridine / pyridine; CH₂Cl₂ / 168 h / 40 °C

With pyridine; dmap; sodium tetrahydroborate; osmium(VIII) oxide; oxalyl dichloride; water; hydrogen; acetic acid; dimethyl sulfoxide; 4-methylmorpholine N-oxide; triethylamine; palladium hydroxide - carbon; In tetrahydrofuran; pyridine; methanol; ethanol; dichloromethane; water; tert-butyl alcohol;

DOI:10.1016/S0008-6215(00)90006-5

upstream raw materials:

2-Methoxypropene

(4aR,6S,7R,8aS)-8-[2-Hydroxy-eth-(E)-ylidene]-6-methoxy-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-7-ol

Downstream raw materials:

methyl 4,6-O-benzylidene-3-C-<(R)-1,2-dihydroxyethyl>-2,2¹-O-isopropylidene-α-D-glucopyranoside

Acetic acid (4aR,6S,6aR,11S,11aS,11bR)-11a-hydroxy-6-methoxy-8,8-dimethyl-2-phenyl-octahydro-1,3,5,7,9-pentaoxa-cyclohepta[a]naphthalen-11-yl ester

methyl 1¹-O-acetyl-3-C-<(S)-1,2-dihydroxyethyl>-2,2¹-O-isopropylidene-6-O-pivaloyl-4-O-p-tolylsulfonyl-α-D-glucopyranoside

methyl 4,6-O-benzylidene-3-C-<(S)-1,2-dihydroxyethyl>-2,2¹-O-isopropylidene-α-D-glucopyranoside

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 110889-27-5 methyl 4,6-O-benzylidene-3-C-<(Z)-2-hydroxyethylidene>-2,2¹-O-isopropylidene-α-D-ribo-hexopyranoside

Send

Send

Metric Ton KG G Pound L ML

Send

Send