(anti)-methyl 3-(m-chlorophenyl)-2-[(diphenylmethylene)amino]-3-(p-toluenesulfonylamino)propanoate

Base Information

Chemical Name:(anti)-methyl 3-(m-chlorophenyl)-2-[(diphenylmethylene)amino]-3-(p-toluenesulfonylamino)propanoate
CAS No.:1073118-19-0
Molecular Formula:C₃₀H₂₇ClN₂O₄S
Molecular Weight:547.074
Hs Code.:

Synonyms:(anti)-methyl 3-(m-chlorophenyl)-2-[(diphenylmethylene)amino]-3-(p-toluenesulfonylamino)propanoate

Suppliers and Price of (anti)-methyl 3-(m-chlorophenyl)-2-[(diphenylmethylene)amino]-3-(p-toluenesulfonylamino)propanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (anti)-methyl 3-(m-chlorophenyl)-2-[(diphenylmethylene)amino]-3-(p-toluenesulfonylamino)propanoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (anti)-methyl 3-(m-chlorophenyl)-2-[(diphenylmethylene)amino]-3-(p-toluenesulfonylamino)propanoate

There total 3 articles about (anti)-methyl 3-(m-chlorophenyl)-2-[(diphenylmethylene)amino]-3-(p-toluenesulfonylamino)propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 81167-39-7
methyl N-(diphenylmethylene)glycinate

: 169829-11-2
N-(m-chlorobenzylidene)-4-methylbenzenesulfonamide

: 1073118-19-0
(anti)-methyl 3-(m-chlorophenyl)-2-[(diphenylmethylene)amino]-3-(p-toluenesulfonylamino)propanoate

Guidance literature:: With tetrakis(acetonitrile)copper(I) perchlorate; C₃₀H₃₂FeNO₃P; triethylamine; In tetrahydrofuran; at -78 ℃; optical yield given as %ee; diastereoselective reaction; Inert atmosphere; Molecular sieve;
DOI:10.1021/ja804527r

Reference yield:

: 81167-39-7
methyl N-(diphenylmethylene)glycinate

: 169829-11-2
N-(m-chlorobenzylidene)-4-methylbenzenesulfonamide

: 1073118-19-0
(anti)-methyl 3-(m-chlorophenyl)-2-[(diphenylmethylene)amino]-3-(p-toluenesulfonylamino)propanoate

: 1251548-16-9
methyl 2-[(diphenylmethylene)amino]-3-(4-methylphenylsulfonamide)-3-(m-chlorophenyl)propanoate

: methyl 2-[(diphenylmethylene)amino]-3-(4-methylphenylsulfonamide)-3-(m-chlorophenyl)propanoate

: (syn)-methyl 3-(m-chlorophenyl)-2-[(diphenylmethylene)amino]-3-(p-toluenesulfonylamino)propanoate

Guidance literature:: With silver trifluoromethanesulfonate; (3,5-Dioxa-4-phospha-cyclohepta[2,1-a;3,4-a']dinaphthalen-4-yl)-bis-((R)-1-phenyl-ethyl)-amine; In toluene; at 20 ℃; for 24h; Overall yield = 42 %; Overall yield = 27.6 mg; enantioselective reaction;
DOI:10.1016/j.tetasy.2014.11.009

Reference yield:

: 81167-39-7
methyl N-(diphenylmethylene)glycinate

: 169829-11-2
N-(m-chlorobenzylidene)-4-methylbenzenesulfonamide

: 1073118-19-0
(anti)-methyl 3-(m-chlorophenyl)-2-[(diphenylmethylene)amino]-3-(p-toluenesulfonylamino)propanoate

: methyl 2-[(diphenylmethylene)amino]-3-(m-chlorophenyl)-3-(p-toluenesulfonylamino)propanoate

Guidance literature:: N-(m-chlorobenzylidene)-4-methylbenzenesulfonamide; With C₂₅H₃₀Br₂N₄O₄; copper(II) acetate monohydrate; In tetrahydrofuran; at 0 ℃; for 0.25h; Inert atmosphere;

methyl N-(diphenylmethylene)glycinate; In tetrahydrofuran; at 0 ℃; for 26h; optical yield given as %ee; enantioselective reaction; Inert atmosphere;
DOI:10.1002/chem.200900118