(4,5-Dibromo-1H-pyrrol-2-yl)(phenyl)methanone

Base Information

Chemical Name:(4,5-Dibromo-1H-pyrrol-2-yl)(phenyl)methanone
CAS No.:50372-61-7
Molecular Formula:C11H7Br2NO
Molecular Weight:328.991
Hs Code.:2933990090
European Community (EC) Number:700-338-5
DSSTox Substance ID:DTXSID00512870
Nikkaji Number:J481.740K
Wikidata:Q72463900
Mol file:50372-61-7.mol

Synonyms:50372-61-7;(4,5-Dibromo-1H-pyrrol-2-yl)(phenyl)methanone;2,3-dibromo-5-benzoylpyrrole;(4,5-dibromo-1H-pyrrol-2-yl)-phenylmethanone;5-BENZOYL-2,3-DIBROMO-1H-PYRROLE;4,5-DIBROMO-2-BENZOYLPYRROLE;EC 700-338-5;SCHEMBL11003325;DTXSID00512870;MFCD00800227;AKOS015999676;AKOS025394711;HL-0757;SB63291;FT-0721752;NS00004966;J-501335

Suppliers and Price of (4,5-Dibromo-1H-pyrrol-2-yl)(phenyl)methanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
(4,5-Dibromo-1H-pyrrol-2-yl)(phenyl)methanone 95+%
1g
$ 1647.00

Matrix Scientific
(4,5-Dibromo-1H-pyrrol-2-yl)(phenyl)methanone 95+%
250mg
$ 742.00

Crysdot
(4,5-Dibromo-1H-pyrrol-2-yl)(phenyl)methanone 95+%
1g
$ 772.00

Chemenu
(4,5-Dibromo-1H-pyrrol-2-yl)(phenyl)methanone 95%
1g
$ 729.00

American Custom Chemicals Corporation
2,3-DIBROMO-5-BENZOYLPYRROLE 95.00%
5MG
$ 504.66

Alichem
(4,5-Dibromo-1H-pyrrol-2-yl)(phenyl)methanone
1g
$ 665.68

AK Scientific
(4,5-Dibromo-1H-pyrrol-2-yl)(phenyl)methanone
250mg
$ 1051.00

Total 52 raw suppliers

Chemical Property of (4,5-Dibromo-1H-pyrrol-2-yl)(phenyl)methanone

Chemical Property:

Boiling Point:430.963 °C at 760 mmHg
Flash Point:214.439 °C
PSA：32.86000
Density:1.846 g/cm³
LogP:3.77070
Storage Temp.:2-8°C
XLogP3:4.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:328.88739
Heavy Atom Count:15
Complexity:241

Purity/Quality:

99%, ^*data from raw suppliers

(4,5-Dibromo-1H-pyrrol-2-yl)(phenyl)methanone 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C(=O)C2=CC(=C(N2)Br)Br
Uses 4,5-Dibromo-2-benzoylpyrrole is used in preparation of 2,3-Dibromo-5-benzoyl Pyrrole via amidation of morpholine with Benzoyl Chloride, followed by Friedel-Crafts reaction with pyrrole and substitution with Br2.

Technology Process of (4,5-Dibromo-1H-pyrrol-2-yl)(phenyl)methanone

There total 2 articles about (4,5-Dibromo-1H-pyrrol-2-yl)(phenyl)methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 7697-46-3
phenyl(1H-pyrrol-2-yl)methanone

: 50372-61-7
2,3-dibromo-5-benzoylpyrrole

Guidance literature:: With copper(ll) bromide; In acetonitrile; for 48h; Ambient temperature;

Reference yield:

: 50372-61-7
2,3-dibromo-5-benzoylpyrrole

Guidance literature:: entspr. Pyrrol, Br2-AcOH;

Reference yield:

: 50372-61-7
2,3-dibromo-5-benzoylpyrrole

: 74103-06-3
Ketorolac

Guidance literature:: Multi-step reaction with 4 steps

1: 1.) NaH / 1.) DMF, RT, 1 h, 2.) 75-80 deg C, 4 h

2: HCl / 5 h / 0 deg C to RT

4: magnesium oxide, H₂ / 5percent Pd/C / H₂O; methanol / 2 h / 760 Torr / Ambient temperature

With hydrogenchloride; hydrogen; magnesium oxide; sodium hydride; palladium on activated charcoal; In methanol; water;
DOI:10.1021/jo00348a014