(2S,4S,5S,6E,8E,10E)-12-(4-methoxybenzyloxy)-5-(methoxymethoxy)-2,4,10-trimethyldodeca-6,8,10-trienal

Base Information

Chemical Name:(2S,4S,5S,6E,8E,10E)-12-(4-methoxybenzyloxy)-5-(methoxymethoxy)-2,4,10-trimethyldodeca-6,8,10-trienal
CAS No.:910043-30-0
Molecular Formula:C₂₅H₃₆O₅
Molecular Weight:416.558
Hs Code.:

Synonyms:(2S,4S,5S,6E,8E,10E)-12-(4-methoxybenzyloxy)-5-(methoxymethoxy)-2,4,10-trimethyldodeca-6,8,10-trienal

Suppliers and Price of (2S,4S,5S,6E,8E,10E)-12-(4-methoxybenzyloxy)-5-(methoxymethoxy)-2,4,10-trimethyldodeca-6,8,10-trienal

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2S,4S,5S,6E,8E,10E)-12-(4-methoxybenzyloxy)-5-(methoxymethoxy)-2,4,10-trimethyldodeca-6,8,10-trienal

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2S,4S,5S,6E,8E,10E)-12-(4-methoxybenzyloxy)-5-(methoxymethoxy)-2,4,10-trimethyldodeca-6,8,10-trienal

There total 17 articles about (2S,4S,5S,6E,8E,10E)-12-(4-methoxybenzyloxy)-5-(methoxymethoxy)-2,4,10-trimethyldodeca-6,8,10-trienal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 910043-13-9
(2S,4S,5S,6E,8E,10E)-12-(4-methoxybenzyloxy)-5-(methoxymethoxy)-2,4,10-trimethyldodeca-6,8,10-trien-1-ol

: 910043-30-0
(2S,4S,5S,6E,8E,10E)-12-(4-methoxybenzyloxy)-5-(methoxymethoxy)-2,4,10-trimethyldodeca-6,8,10-trienal

Guidance literature:: With oxalyl dichloride; dimethyl sulfoxide; triethylamine; In dichloromethane; at -78 - 20 ℃;
DOI:10.1021/ja0581346

Reference yield:

: 136786-39-5
benzyl [6-(tert-butyldiphenylsilyloxy)-3(S),5(S)-dimethyl-2(S)-(methoxymethoxy)hex-1-yl] ether

: 910043-30-0
(2S,4S,5S,6E,8E,10E)-12-(4-methoxybenzyloxy)-5-(methoxymethoxy)-2,4,10-trimethyldodeca-6,8,10-trienal

Guidance literature:: Multi-step reaction with 5 steps

1.1: 86 percent / hydrogen / Pd/C / ethanol / 760 Torr

2.1: 100 percent / oxalyl chloride; DMSO; triethylamine / CH₂Cl₂ / 0.67 h / -78 - 20 °C

3.1: HMPA; nBuLi / tetrahydrofuran; petroleum ether / 0.17 h / cooling

3.2: 92 percent / tetrahydrofuran; petroleum ether / 1.17 h / -78 - 20 °C

4.1: 99 percent / tetrabutylammonium fluoride / tetrahydrofuran / 3 h / 20 °C

5.1: 100 percent / oxalyl chloride; DMSO; triethylamine / CH₂Cl₂ / -78 - 20 °C

With N,N,N,N,N,N-hexamethylphosphoric triamide; n-butyllithium; oxalyl dichloride; tetrabutyl ammonium fluoride; hydrogen; dimethyl sulfoxide; triethylamine; palladium on activated charcoal; In tetrahydrofuran; ethanol; dichloromethane; Petroleum ether; 2.1: Swern oxidation / 3.2: Horner-Wadsworth-Emmons olefination / 5.1: Swern oxidation;
DOI:10.1021/ja0581346

Reference yield:

: 136786-36-2
(2S,3S,5S)-1-(benzyloxy)-6-(tert-butyldiphenylsilyloxy)-3,5-dimethylhexan-2-ol

: 910043-30-0
(2S,4S,5S,6E,8E,10E)-12-(4-methoxybenzyloxy)-5-(methoxymethoxy)-2,4,10-trimethyldodeca-6,8,10-trienal

Guidance literature:: Multi-step reaction with 6 steps

1.1: 89 percent / iPr₂NEt; TBAI / CH₂Cl₂ / 48 h / 20 °C

2.1: 86 percent / hydrogen / Pd/C / ethanol / 760 Torr

3.1: 100 percent / oxalyl chloride; DMSO; triethylamine / CH₂Cl₂ / 0.67 h / -78 - 20 °C

4.1: HMPA; nBuLi / tetrahydrofuran; petroleum ether / 0.17 h / cooling

4.2: 92 percent / tetrahydrofuran; petroleum ether / 1.17 h / -78 - 20 °C

5.1: 99 percent / tetrabutylammonium fluoride / tetrahydrofuran / 3 h / 20 °C

6.1: 100 percent / oxalyl chloride; DMSO; triethylamine / CH₂Cl₂ / -78 - 20 °C

With N,N,N,N,N,N-hexamethylphosphoric triamide; n-butyllithium; oxalyl dichloride; tetrabutyl ammonium fluoride; hydrogen; tetra-(n-butyl)ammonium iodide; dimethyl sulfoxide; triethylamine; N-ethyl-N,N-diisopropylamine; palladium on activated charcoal; In tetrahydrofuran; ethanol; dichloromethane; Petroleum ether; 3.1: Swern oxidation / 4.2: Horner-Wadsworth-Emmons olefination / 6.1: Swern oxidation;
DOI:10.1021/ja0581346