8-(3,3-dimethylallyl)-5,7,3',4'-tetrakis(methoxymethoxy)flavanone

Base Information

• Chemical Name: 8-(3,3-dimethylallyl)-5,7,3',4'-tetrakis(methoxymethoxy)flavanone
• CAS No.: 132246-43-6
• Molecular Formula: C₂₈H₃₆O₁₀
• Molecular Weight: 532.588
• Mol file: 132246-43-6.mol

Synonyms:8-(3,3-dimethylallyl)-5,7,3',4'-tetrakis(methoxymethoxy)flavanone

Chemical Property of 8-(3,3-dimethylallyl)-5,7,3',4'-tetrakis(methoxymethoxy)flavanone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 8-(3,3-dimethylallyl)-5,7,3',4'-tetrakis(methoxymethoxy)flavanone

There total 7 articles about 8-(3,3-dimethylallyl)-5,7,3',4'-tetrakis(methoxymethoxy)flavanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

2-methyl-but-2-ene (513-35-9) + 8-allyl-5,7-bis(methoxymethoxy)-2-(3,4-bis(methoxymethoxy)phenyl)chroman-4-one → 8-(3,3-dimethylallyl)-5,7,3',4'-tetrakis(methoxymethoxy)flavanone (132246-43-6)

Guidance literature:

With tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride; In dichloromethane; at 20 ℃; for 16h;

DOI:10.1002/ejoc.202001378

Reference yield: 51.0%

5'-(3,3-dimethylallyl)-6'-hydroxy-3,4,2',4'-tetrakis(methoxymethoxy)chalcone (132246-42-5) → 8-(3,3-dimethylallyl)-5,7,3',4'-tetrakis(methoxymethoxy)flavanone (132246-43-6)

Guidance literature:

With sodium acetate; In methanol; at 50 ℃; for 20h;

Reference yield:

3,4-bis-methoxymethoxy-benzaldehyde (6515-06-6) → 8-(3,3-dimethylallyl)-5,7,3',4'-tetrakis(methoxymethoxy)flavanone (132246-43-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 56.5 percent / 28percent NaOMe / methanol / 6 h / Ambient temperature

2: 51 percent / NaOAc / methanol / 20 h / 50 °C

With sodium methylate; sodium acetate; In methanol;

upstream raw materials:

5'-(3,3-dimethylallyl)-6'-hydroxy-3,4,2',4'-tetrakis(methoxymethoxy)chalcone

3,4-bis-methoxymethoxy-benzaldehyde

2',4'-bis(methoxymethoxy)-5'-(3,3-dimethylallyl)-6'-hydroxyacetophenone

C₂₈H₃₆O₁₀

Downstream raw materials:

8-(3,3-dimethylallyl)-5,7,3',4'-tetrahydroxyflavanone

6,6-dimethyl-4,5-dihydropyrano(2,3:7,8)-5,3',4'-trihydroxyflavanone

8-(3-hydroxyisoamyl)-5,7,3',4'-tetrahydroxyflavanone

8-(3-methoxyisoamyl)-5,7,3',4'-tetrahydroxyflavanone