Technology Process of trimethyl-(2,3-dimethyl-3-phenylcycloprop-1-enyl)silane
There total 6 articles about trimethyl-(2,3-dimethyl-3-phenylcycloprop-1-enyl)silane which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
trimethyl-(3-methyl-3-phenylcycloprop-1-enyl)silane;
With
n-butyllithium;
In
tetrahydrofuran; hexane;
at -78 - -30 ℃;
methyl iodide;
In
tetrahydrofuran; hexane;
at -78 - 20 ℃;
Further stages.;
DOI:10.1021/ja027095k
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: 85 percent / EtMgBr / Ti(Oi-Pr)4 / diethyl ether / 1.67 h / 20 °C
2.1: 79 percent / t-BuOK / dimethylsulfoxide / 10 h / 20 °C
3.1: n-butyllithium / diethyl ether; hexane / 2 h / -78 °C
4.1: 45.26 g / diethyl ether; hexane / 10 h / -78 - 0 °C
5.1: n-BuLi / tetrahydrofuran; hexane / -78 - -30 °C
5.2: 81 percent / tetrahydrofuran; hexane / -78 - 20 °C
With
n-butyllithium; ethylmagnesium bromide; potassium tert-butylate;
titanium(IV) isopropylate;
In
tetrahydrofuran; diethyl ether; hexane; dimethyl sulfoxide;
DOI:10.1021/ja027095k
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: 92 percent / cetrimide; aq. NaOH / 30 h / 35 - 40 °C
2.1: 85 percent / EtMgBr / Ti(Oi-Pr)4 / diethyl ether / 1.67 h / 20 °C
3.1: 79 percent / t-BuOK / dimethylsulfoxide / 10 h / 20 °C
4.1: n-butyllithium / diethyl ether; hexane / 2 h / -78 °C
5.1: 45.26 g / diethyl ether; hexane / 10 h / -78 - 0 °C
6.1: n-BuLi / tetrahydrofuran; hexane / -78 - -30 °C
6.2: 81 percent / tetrahydrofuran; hexane / -78 - 20 °C
With
sodium hydroxide; n-butyllithium; ethylmagnesium bromide; potassium tert-butylate; cetyltrimethylammonim bromide;
titanium(IV) isopropylate;
In
tetrahydrofuran; diethyl ether; hexane; dimethyl sulfoxide;
DOI:10.1021/ja027095k
