3',5'-di-O-benzyl-2'-O-(2,3-di-O-benzyl-4-O-stearoyl-α-L-fucopyranosyl)thymidine

Base Information

Chemical Name:3',5'-di-O-benzyl-2'-O-(2,3-di-O-benzyl-4-O-stearoyl-α-L-fucopyranosyl)thymidine
CAS No.:201348-65-4
Molecular Formula:C₆₂H₈₂N₂O₁₁
Molecular Weight:1031.34
Hs Code.:

Synonyms:3',5'-di-O-benzyl-2'-O-(2,3-di-O-benzyl-4-O-stearoyl-α-L-fucopyranosyl)thymidine

Suppliers and Price of 3',5'-di-O-benzyl-2'-O-(2,3-di-O-benzyl-4-O-stearoyl-α-L-fucopyranosyl)thymidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3',5'-di-O-benzyl-2'-O-(2,3-di-O-benzyl-4-O-stearoyl-α-L-fucopyranosyl)thymidine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3',5'-di-O-benzyl-2'-O-(2,3-di-O-benzyl-4-O-stearoyl-α-L-fucopyranosyl)thymidine

There total 8 articles about 3',5'-di-O-benzyl-2'-O-(2,3-di-O-benzyl-4-O-stearoyl-α-L-fucopyranosyl)thymidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 201348-48-3
1-(3',5'-di-O-benzyl-β-D-ribo-furanosyl)thymine

: 201348-64-3
2-(2,3-di-O-benzyl-4-O-stearoyl-β-L-fucopyranosylsulfanyl)pyrimidine

: 201348-65-4
3',5'-di-O-benzyl-2'-O-(2,3-di-O-benzyl-4-O-stearoyl-α-L-fucopyranosyl)thymidine

Guidance literature:: With trimethylsilyl trifluoromethanesulfonate; In dichloromethane; for 5h; Ambient temperature;
DOI:10.1016/S0960-894X(97)10116-0

Reference yield:

: 100-39-0
benzyl bromide

: 201348-65-4
3',5'-di-O-benzyl-2'-O-(2,3-di-O-benzyl-4-O-stearoyl-α-L-fucopyranosyl)thymidine

Guidance literature:: Multi-step reaction with 3 steps

1.1: Bu₂SnO / methanol / 1 h / Heating

1.2: 71 percent / Bu₄NI / toluene / 18 h / 50 °C

2.1: 90 percent / pyridine / 3 h / 20 °C

3.1: 88 percent / TMSOTf / CH₂Cl₂ / 3 h / 20 °C

With pyridine; trimethylsilyl trifluoromethanesulfonate; di(n-butyl)tin oxide; In methanol; dichloromethane;
DOI:10.1016/S0008-6215(02)00356-7

Reference yield:

: 100-39-0
benzyl bromide

: 201348-65-4
3',5'-di-O-benzyl-2'-O-(2,3-di-O-benzyl-4-O-stearoyl-α-L-fucopyranosyl)thymidine

Guidance literature:: Multi-step reaction with 3 steps

1: 71 percent / dibutyltin oxide, tetrabutylammonium iodide / methanol; toluene

2: 90 percent / pyridine / 1 h / Ambient temperature

3: 90 percent / TMSOTf / CH₂Cl₂ / 5 h / Ambient temperature

With trimethylsilyl trifluoromethanesulfonate; tetra-(n-butyl)ammonium iodide; di(n-butyl)tin oxide; In pyridine; methanol; dichloromethane; toluene;
DOI:10.1016/S0960-894X(97)10116-0