5-nitro-2-phenoxythiophene

Base Information

• Chemical Name: 5-nitro-2-phenoxythiophene
• CAS No.: 190966-67-7
• Molecular Formula: C₁₀H₇NO₃S
• Molecular Weight: 221.236
• Mol file: 190966-67-7.mol

Synonyms:5-nitro-2-phenoxythiophene

Chemical Property of 5-nitro-2-phenoxythiophene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-nitro-2-phenoxythiophene

There total 3 articles about 5-nitro-2-phenoxythiophene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

2-bromo-5-nitrothiophene (13195-50-1,76216-72-3) + phenol (108-95-2,27073-41-2) → 5-nitro-2-phenoxythiophene (190966-67-7)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 70 ℃; for 5h;

DOI:10.1016/S0968-0896(97)00025-4

Reference yield:

2-bromo-5-nitrothiophene (13195-50-1,76216-72-3) + potassium phenolate (100-67-4) → 5-nitro-2-phenoxythiophene (190966-67-7)

Guidance literature:

In 1,4-dioxane; for 2h; Heating;

DOI:10.1021/jo060435q

Reference yield:

→ 5-nitro-2-phenoxythiophene (190966-67-7)

Guidance literature:

upstream raw materials:

2-bromo-5-nitrothiophene

phenol

potassium phenolate

Downstream raw materials:

2-acetamido-5-phenoxy thiophene