4-chlorophenyl dithioacetate

Base Information

• Chemical Name: 4-chlorophenyl dithioacetate
• CAS No.: 193765-63-8
• Molecular Formula: C₈H₇ClS₂
• Molecular Weight: 202.729
• Mol file: 193765-63-8.mol

Synonyms:4-chlorophenyl dithioacetate

Chemical Property of 4-chlorophenyl dithioacetate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-chlorophenyl dithioacetate

There total 2 articles about 4-chlorophenyl dithioacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

p-Chlorothiophenol (106-54-7) → 4-chlorophenyl dithioacetate (193765-63-8)

Guidance literature:

Multi-step reaction with 2 steps

1: diethyl ether / 0 - 5 °C

2: Lawesson's reagent

With Lawessons reagent; In diethyl ether;

DOI:10.1021/jo970413r

Reference yield:

S-acetyl-4-chlorothiophenol (21021-60-3) → 4-chlorophenyl dithioacetate (193765-63-8)

Guidance literature:

With Lawessons reagent;

DOI:10.1021/jo970413r

Reference yield:

aniline (62-53-3) + 4-chlorophenyl dithioacetate (193765-63-8) → thioacetanilide (637-53-6)

Guidance literature:

In acetonitrile; at 50 ℃; Rate constant; Mechanism; aminolysis of phenyl dithioacetates with anilines, N,N-dimethylanilines and benzylamines in MeCN; formation of zwitterionic tetrahedral intermediate; proton transfer; rate-limiting step; effect of nucleophile, leaving group;

DOI:10.1021/jo970413r

upstream raw materials:

S-acetyl-4-chlorothiophenol

p-Chlorothiophenol

Downstream raw materials:

N-(p-tolyl)ethanethioamide

N-(4-chlorophenyl)ethanethioamide

N-(4-methoxyphenyl)thioacetamide

N-p-Methoxybenzyl-thioacetamid