(R)-<3-<4-(methylthio)phenyl>-2-oxo-5-oxazolidinyl>methyl 4-methylbenzenesulfonate

Base Information

Chemical Name:(R)-<3-<4-(methylthio)phenyl>-2-oxo-5-oxazolidinyl>methyl 4-methylbenzenesulfonate
CAS No.:121373-24-8
Molecular Formula:C₁₈H₁₉NO₅S₂
Molecular Weight:393.485
Hs Code.:

Synonyms:(R)-<3-<4-(methylthio)phenyl>-2-oxo-5-oxazolidinyl>methyl 4-methylbenzenesulfonate

Suppliers and Price of (R)-<3-<4-(methylthio)phenyl>-2-oxo-5-oxazolidinyl>methyl 4-methylbenzenesulfonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (R)-<3-<4-(methylthio)phenyl>-2-oxo-5-oxazolidinyl>methyl 4-methylbenzenesulfonate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (R)-<3-<4-(methylthio)phenyl>-2-oxo-5-oxazolidinyl>methyl 4-methylbenzenesulfonate

There total 4 articles about (R)-<3-<4-(methylthio)phenyl>-2-oxo-5-oxazolidinyl>methyl 4-methylbenzenesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 1632-84-4
4-(methylthio)phenyl isocyanate

: 113826-06-5,6746-81-2
(R)-glycidyl tosylate

: 121373-24-8
(R)-<3-<4-(methylthio)phenyl>-2-oxo-5-oxazolidinyl>methyl 4-methylbenzenesulfonate

Guidance literature:: With lithium iodide; In tetrahydrofuran; for 0.5h; regioselective reaction; Reflux;
DOI:10.5012/bkcs.2011.32.12.4450

Reference yield: 74.0%

: 98-59-9
p-toluenesulfonyl chloride

: 82796-40-5
5(R)-hydroxymethyl-3-(4-methylthiophenyl)oxazolidin-2-one

: 121373-24-8
(R)-<3-<4-(methylthio)phenyl>-2-oxo-5-oxazolidinyl>methyl 4-methylbenzenesulfonate

Guidance literature:: With pyridine; at 15 ℃;
DOI:10.1021/jm00128a003

Reference yield:

: 1632-84-4
4-(methylthio)phenyl isocyanate

: 121373-24-8
(R)-<3-<4-(methylthio)phenyl>-2-oxo-5-oxazolidinyl>methyl 4-methylbenzenesulfonate

Guidance literature:: Multi-step reaction with 3 steps

1: 100 percent / LiBr, n-Bu₃PO / xylene / 2 h / Heating

2: 100 percent / sodium methoxide / methanol / 2 h / Ambient temperature

3: 74 percent / pyridine / 15 °C

With pyridine; Tributylphosphine oxide; sodium methylate; lithium bromide; In methanol; xylene;
DOI:10.1021/jm00128a003