Diphenylmethyl (alphaR,2R)-2-(2-benzothiazolyldithio)-alpha-(1-methylethenyl)-4-oxo-1-azetidineacetate

Base Information Edit

Chemical Name:Diphenylmethyl (alphaR,2R)-2-(2-benzothiazolyldithio)-alpha-(1-methylethenyl)-4-oxo-1-azetidineacetate
CAS No.:87579-79-1
Molecular Formula:C₂₈H₂₄N₂O₃S₃
Molecular Weight:532.708
Hs Code.:
European Community (EC) Number:618-032-4
DSSTox Substance ID:DTXSID501118001
Nikkaji Number:J381.705I
Mol file:87579-79-1.mol

Synonyms:SCHEMBL23067213;DTXSID501118001;(2R)-2-[(2R)-2-[(Benzothiazol-2-yl)dithio]-4-oxoazetidin-1-yl]-3-methyl-3-butenoic acid benzhydryl ester;87579-79-1;Diphenylmethyl (alphaR,2R)-2-(2-benzothiazolyldithio)-alpha-(1-methylethenyl)-4-oxo-1-azetidineacetate

Suppliers and Price of Diphenylmethyl (alphaR,2R)-2-(2-benzothiazolyldithio)-alpha-(1-methylethenyl)-4-oxo-1-azetidineacetate

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(αR,2R)-2-(2-Benzothiazolyldithio)-α-(1-methylethenyl)-4-oxo-1-azetidineaceticAcidDiphenylmethylEster
500mg
$ 930.00

TRC
(αR,2R)-2-(2-Benzothiazolyldithio)-α-(1-methylethenyl)-4-oxo-1-azetidineaceticAcidDiphenylmethylEster
250mg
$ 480.00

Total 4 raw suppliers

Chemical Property of Diphenylmethyl (alphaR,2R)-2-(2-benzothiazolyldithio)-alpha-(1-methylethenyl)-4-oxo-1-azetidineacetate Edit

Chemical Property:

XLogP3:7.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:10
Exact Mass:532.09490615
Heavy Atom Count:36
Complexity:781

Purity/Quality:

98.5% ^*data from raw suppliers

(αR,2R)-2-(2-Benzothiazolyldithio)-α-(1-methylethenyl)-4-oxo-1-azetidineaceticAcidDiphenylmethylEster ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(=C)C(C(=O)OC(C1=CC=CC=C1)C2=CC=CC=C2)N3C(CC3=O)SSC4=NC5=CC=CC=C5S4
Isomeric SMILES:CC(=C)[C@H](C(=O)OC(C1=CC=CC=C1)C2=CC=CC=C2)N3[C@@H](CC3=O)SSC4=NC5=CC=CC=C5S4
Uses (αR,2R)-2-(2-Benzothiazolyldithio)-α-(1-methylethenyl)-4-oxo-1-azetidineacetic Acid Diphenylmethyl Ester is used in the synthesis of 4-Sulfonylazetidin-2-ones which exhibits anti-cancer effects;Also, it is an intermediate used in the synthesis of Tazobactam Sodium Salt-15N3 (T010103), which is a labeled analogue of Tazobactam Sodium Salt (T010100), which is a β-Lactamase inhibitor, used with β-lactam antibiotics to enhance their effect.

Technology Process of Diphenylmethyl (alphaR,2R)-2-(2-benzothiazolyldithio)-alpha-(1-methylethenyl)-4-oxo-1-azetidineacetate

There total 20 articles about Diphenylmethyl (alphaR,2R)-2-(2-benzothiazolyldithio)-alpha-(1-methylethenyl)-4-oxo-1-azetidineacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%